Evidence map›Paper›PMID 40806447›Full record

ReviewInternational journal of molecular sciences2025

Food-Derived Phytochemicals: Multicultural Approaches to Oxidative Stress and Immune Response.

Eiger Gliozheni, Yusuf Salem, Eric Cho, Samuel Wahlstrom, Dane Olbrich, Brandon Shams, Michael Alexander, Hirohito Ichii

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Antioxidants (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eiger GliozheniDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.
Yusuf SalemDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.ORCID 0009-0002-5155-6925
Eric ChoDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.ORCID 0009-0008-2372-6206
Samuel WahlstromDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.
Dane OlbrichDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.
Brandon ShamsDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.ORCID 0009-0003-1414-497X
Michael AlexanderDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.ORCID 0000-0001-7793-394X
Hirohito IchiiDepartment of Surgery, University of California Irvine, Orange, CA 92868, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review will focus on how ethnic consumption of foods such as shiitake, ginseng, turmeric, black seeds, berries, rosemary, moringa and holy basil can help act as antioxidants and immune modulators in fighting many diseases. We will investigate how these foods act on pathways like Nrf2/Keap1 to increase endogenous antioxidant capacity and help in reducing ROS production, based on publications found in PubMed between 1994 and 2024. In addition, we will show how these plants can cause immune system shifts by changing the makeup of the ratio of Th1/Th2 cells, reduce inflammation, and have antiangiogenic effects on cancer. This review will also show how plants can alter the gut microbiota and lead to a further decrease in oxidative stress. Overall, it will show how plants and their metabolites can potentially create a path forward for creating novel therapeutic approaches and help lead to an improved redox balance, support immune function, and enhance long-term health outcomes.

Indexed as

ImmunityOxidative StressPhytochemicalsAnimalsAntioxidantsGastrointestinal MicrobiomeHumansAntioxidantsPhytochemicalsantioxidantinflammationNrf2/Keap1 pathwayoxidative stressTh1/Th2 ratio

Identifiers

PMID40806447
PMCPMC12347654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.