ArticleInternational journal of molecular sciences2025
The Role of Mutations, Addition of Amino Acids, and Exchange of Genetic Information in the Coevolution of Primitive Coding Systems.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The standard genetic code (SGC) plays a fundamental role in encoding biological information, but its evolutionary origins remain unresolved and widely debated. Thus, we used a methodology based on the evolutionary algorithm to investigate the emergence of stable coding systems. The simulation began with a population of varied primitive genetic codes that ambiguously encoded only a limited set of amino acids (labels). These codes underwent mutation, modeled by dynamic reassignment of labels to codons, gradual incorporation of new amino acids, and information exchange between themselves. Then, the best codes were selected using a specific fitness function
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