Evidence map›Paper›PMID 40806251›Full record

ArticleInternational journal of molecular sciences2025

Eurycomanone Blocks TGF-β1-Induced Epithelial-to-Mesenchymal Transition, Migration, and Invasion Pathways in Human Non-Small Cell Lung Cancer Cells by Targeting Smad and Non-Smad Signaling.

Pratchayanon Soddaen, Kongthawat Chairatvit, Pornsiri Pitchakarn, Tanongsak Laowanitwattana, Arisa Imsumran, Ariyaphong Wongnoppavich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pratchayanon SoddaenGraduate/M.Sc. Program in Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Kongthawat ChairatvitDepartment of Oral Biology, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Pornsiri PitchakarnDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-6219-386X
Tanongsak LaowanitwattanaDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Arisa ImsumranDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-2787-2461
Ariyaphong WongnoppavichDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-9238-0447

Funding

Faculty of Medicine Research Fund, Chiang Mai University 068-2565
6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) is a predominant form of lung cancer that is often diagnosed at an advanced metastatic stage. The processes of cancer cell migration and invasion involve epithelial-to-mesenchymal transition (EMT), which is crucial for metastasis. Targeting cancer aggressiveness with effective plant compounds has gained attention as a potential adjuvant therapy. Eurycomanone (ECN), a bioactive quassinoid found in the root of

Indexed as

Carcinoma, Non-Small-Cell LungCell MovementEpithelial-Mesenchymal TransitionLung NeoplasmsQuassinsSignal TransductionSmad ProteinsTransforming Growth Factor beta1A549 CellsCell Line, TumorHumansNeoplasm InvasivenessQuassinsSmad ProteinsTransforming Growth Factor beta1epithelial-to-mesenchymal transitioneurycomalactoneeurycomanoneinvasionnon-small cell lung cancer

Identifiers

PMID40806251
PMCPMC12345748

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.