Evidence map›Paper›PMID 40806237›Full record

ArticleInternational journal of molecular sciences2025

Large-Scale Profiling of Coding and Long Noncoding Transcriptomes in the Hippocampus of Mice Acutely Exposed to Vaporized CBD or THC.

Mi Ran Choi, Jihun Kim, Chaeeun Park, Seok Hwan Chang, Han-Na Kim, Yeung Bae Jin, Sang-Rae Lee

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mi Ran ChoiLaboratory Animal Research Center, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Jihun KimEfficacy Test Center for Mental & Behavioral Disorders, Ajou University Hospital, Suwon 16499, Republic of Korea.
Chaeeun ParkEfficacy Test Center for Mental & Behavioral Disorders, Ajou University Hospital, Suwon 16499, Republic of Korea.
Seok Hwan ChangEfficacy Test Center for Mental & Behavioral Disorders, Ajou University Hospital, Suwon 16499, Republic of Korea.
Han-Na KimCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Yeung Bae JinCollege of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0001-6783-7970
Sang-Rae LeeLaboratory Animal Research Center, Ajou University School of Medicine, Suwon 16499, Republic of Korea.

Funding

the Bio&Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) RS-2023-00223559The Korea Bio-health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea RS-2023-00267453The Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea RS-2021-KH113822
6 · The paper itself

Abstract

Cannabis vaping, particularly involving cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC), rapidly delivers highly concentrated cannabinoids to the brain, potentially affecting the hippocampus. This study examined differential expression of long noncoding RNAs (lncRNAs) and mRNAs in the hippocampus after acute exposure to vaporized CBD or THC. Male ICR mice were exposed to vaporized CBD or THC (50 mg, n = 5/group), and hippocampal tissues were collected at 1, 3, and 14 days post-exposure. Total RNA sequencing was conducted on day 1 samples, and selected transcripts were validated using qRT-PCR across multiple time points. CBD led to significant up- or downregulation of

Indexed as

CannabidiolDronabinolHippocampusRNA, Long NoncodingTranscriptomeAnimalsGene Expression ProfilingGene Expression RegulationMaleMiceMice, Inbred ICRRNA, MessengerCannabidiolDronabinolRNA, Long NoncodingRNA, Messengercannabidioldelta-9-tetrahydrocannabinolhippocampustranscriptomevaping

Identifiers

PMID40806237
PMCPMC12346642

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.