Evidence map›Paper›PMID 40806234›Full record

ArticleInternational journal of molecular sciences2025

What Is Similar, What Is Different? Characterization of Mitoferrin-like Proteins from

Karolina Małas, Ludmiła Polechońska, Katarzyna Kabała

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karolina MałasDepartment of Plant Molecular Physiology, Faculty of Biological Sciences, University of Wrocław, Kanonia 6/8, 50-328 Wroclaw, Poland.
Ludmiła PolechońskaDepartment of Ecology, Biogeochemistry and Environmental Protection, Faculty of Biological Sciences, University of Wrocław, Kanonia 6/8, 50-328 Wroclaw, Poland.
Katarzyna KabałaDepartment of Plant Molecular Physiology, Faculty of Biological Sciences, University of Wrocław, Kanonia 6/8, 50-328 Wroclaw, Poland.ORCID 0000-0003-0421-8018

Funding

Polish National Science Center 2018/29/N/NZ1/01432
6 · The paper itself

Abstract

Chloroplasts, as the organelles primarily responsible for photosynthesis, require a substantial supply of iron ions. Conversely, due to Fe toxicity, the homeostasis of these ions is subject to tight regulation. Permease in chloroplast 1 (PIC1) has been identified as the primary iron importer into chloroplasts. However, previous studies suggested the existence of a distinct pathway for Fe transfer to chloroplasts, likely involving mitoferrin-like 1 (MFL1) protein. In this work, Arabidopsis MFL1 (AtMFL1) and its cucumber homolog (CsMFL1) were characterized using, among others, Arabidopsis protoplasts as well as both yeast and Arabidopsis mutants. Localization of both proteins in chloroplasts has been shown to be mediated via an N-terminal transit peptide. At the gene level,

Indexed as

ArabidopsisArabidopsis ProteinsCucumis sativusPlant ProteinsChloroplastsGene Expression Regulation, PlantIronMutationPhotosynthesisArabidopsis ProteinsIronPlant Proteinschloroplastsiron homeostasisMCFmitoferrin-like proteinsMIT proteins

Identifiers

PMID40806234
PMCPMC12345680

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.