Evidence map›Paper›PMID 40806223›Full record

ArticleInternational journal of molecular sciences2025

Meng Yuan, Da Wo, Yuhang Gong, Ming Lin, En Ma, Weidong Zhu, Dan-Ni Ren

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meng YuanAcademy of Integrative Medicine, College of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.ORCID 0009-0005-6867-2377
Da WoAcademy of Integrative Medicine, College of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Yuhang GongAcademy of Integrative Medicine, College of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Ming LinAcademy of Integrative Medicine, College of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
En MaAcademy of Integrative Medicine, College of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Weidong ZhuAcademy of Integrative Medicine, College of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Dan-Ni RenAcademy of Integrative Medicine, College of Integrative Medicine, Fujian Key Laboratory of Integrative Medicine on Geriatric, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.ORCID 0000-0002-7431-8156

Funding

Scientific Research Foundation for the High-level Talents, Fujian University of Traditional Chinese Medicine X2021002- talent, X2021003-talent, X2024001- talentYouth Science and Technology Innovation Talent Cultivation Program of FJTCM XQB202201
6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Its sustained proliferative signaling poses a major challenge for effective therapeutic intervention. Since CRC originates from aberrantly proliferating crypt cells, limiting proliferation or inducing senescence may offer a promising treatment approach.

Indexed as

Cellular SenescenceColorectal NeoplasmsCyclin-Dependent Kinase Inhibitor p21Drugs, Chinese HerbalGlycopeptidesLyciumSignal TransductionTumor Suppressor Protein p53AnimalsCell Line, TumorCell ProliferationHumansMiceMice, Inbred BALB CXenograft Model Antitumor AssaysCyclin-Dependent Kinase Inhibitor p21Drugs, Chinese HerbalGlycopeptidesTumor Suppressor Protein p53cell cycle arrestcolorectal cancerLycium barbarum glycopeptidep53/p21 signaling pathway

Identifiers

PMID40806223
PMCPMC12345642

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.