Evidence map›Paper›PMID 40806208›Full record

ArticleInternational journal of molecular sciences2025

The Red Shift in Estrogen Research: An Estrogen-Receptor Targeted

Tamás Hlogyik, Noémi Bózsity, Rita Börzsei, Benjámin Kovács, Péter Labos, Csaba Hetényi, Mónika Kiricsi, Ildikó Huliák, Zoltán Kele, Miklós Poór and 4 more

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tamás HlogyikInstitute of Pharmacognosy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.ORCID 0000-0002-7584-4975
Noémi BózsityInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.ORCID 0000-0002-7907-7734
Rita BörzseiDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti út 12, H-7624 Pécs, Hungary.
Benjámin KovácsInstitute of Pharmacognosy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.ORCID 0009-0004-0799-1908
Péter LabosInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
Csaba HetényiDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti út 12, H-7624 Pécs, Hungary.ORCID 0000-0002-8013-971X
Mónika KiricsiDepartment of Biochemistry and Molecular Biology, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary.
Ildikó HuliákDepartment of Biochemistry and Molecular Biology, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary.
Zoltán KeleDepartment of Medicinal Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Miklós PoórDepartment of Laboratory Medicine, Medical School, University of Pécs, Ifjúság útja 13, H-7624 Pécs, Hungary.ORCID 0000-0003-1425-7459
János ErostyákDepartment of Experimental Physics, Faculty of Sciences, University of Pécs, Ifjúság útja 6, H-7624 Pécs, Hungary.
Attila HunyadiInstitute of Pharmacognosy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.ORCID 0000-0003-0074-3472
István ZupkóInstitute of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.ORCID 0000-0003-3243-5300
Erzsébet MernyákInstitute of Pharmacognosy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.ORCID 0000-0003-4494-1817

Funding

nkfih SNN 139323
6 · The paper itself

Abstract

Estradiol (E2) plays an important role in cell proliferation and certain brain functions. To reveal its mechanism of action, its detectability is essential. Only a few fluorescent-labeled hormonally active E2s exist in the literature, and their mechanism of action usually remains unclear. It would be of particular interest to develop novel labeled estradiol derivatives with retained biological activity and improved optical properties. Due to their superior optical characteristics,

Indexed as

Boron CompoundsEstradiolEstrogen Receptor alphaEstrogensFluorescent DyesReceptors, EstrogenBinding SitesHumansMolecular Docking Simulation4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneazaBDPBA compoundBoron CompoundsEstradiolEstrogen Receptor alphaEstrogensFluorescent DyesReceptors, Estrogenaza-BODIPYCuAAC reactiondockingestradiolfluorescent labelingluciferasered-emission

Identifiers

PMID40806208
PMCPMC12346466

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.