Evidence map›Paper›PMID 40806171›Full record

ArticleInternational journal of molecular sciences2025

The Effect of Statin Therapy on Hemorheological Parameters of Patients with Clinically Silent Ischemic Foci of the Brain.

Anna Marcinkowska-Gapińska, Izabela Siemieniak

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anna Marcinkowska-GapińskaDepartment of Biophysics, Poznan University of Medical Sciences, 61-701 Poznan, Poland.ORCID 0000-0002-9180-2644
Izabela SiemieniakRheological Laboratory, Department of Neurology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemorheology is a branch of science that studies and explains the causes of blood flow disorders. In many vascular disorders whole blood viscosity, plasma viscosity, aggregability, and deformability of erythrocytes can be a diagnostic factor. In this paper we analyze whether statin therapy affects hemorheological values in a group of patients with clinically diagnosed silent ischemic foci of the brain (CSVCL). The study includes an analysis of the hemorheological parameter values such as whole blood viscosity, plasma viscosity, and selected biochemical parameters. Aggregability and deformability of erythrocytes were determined using the mathematical Quemada model. Our results indicate a modifying effect of statins on hemorheological parameters.

Indexed as

Brain IschemiaHemorheologyHydroxymethylglutaryl-CoA Reductase InhibitorsAgedBlood ViscosityErythrocyte AggregationErythrocyte DeformabilityErythrocytesFemaleHumansMaleMiddle AgedHydroxymethylglutaryl-CoA Reductase Inhibitorsaggregability of erythrocytesblood viscosityCSVCLdeformability of erythrocyteshemorheologystatin therapy

Identifiers

PMID40806171
PMCPMC12346203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.