Evidence map›Paper›PMID 40806122›Full record

ReviewNutrients2025

The Oral-Gut Microbiota Axis Across the Lifespan: New Insights on a Forgotten Interaction.

Domenico Azzolino, Margherita Carnevale-Schianca, Luigi Santacroce, Marica Colella, Alessia Felicetti, Leonardo Terranova, Roberto Carlos Castrejón-Pérez, Franklin Garcia-Godoy, Tiziano Lucchi, Pier Carmine Passarelli

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Domenico AzzolinoGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.ORCID 0000-0002-4910-7373
Margherita Carnevale-SchiancaRespiratory Unit, Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.ORCID 0009-0004-5673-7914
Luigi SantacroceInterdisciplinary Department of Medicine, Section of Microbiology and Virology, School of Medicine, University Hospital of Bari, 70124 Bari, Italy.ORCID 0000-0001-5671-8124
Marica ColellaInterdisciplinary Department of Medicine, Section of Microbiology and Virology, School of Medicine, University Hospital of Bari, 70124 Bari, Italy.ORCID 0000-0003-0806-4327
Alessia FelicettiDepartment of Medical and Surgical Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0009-0004-8602-9986
Leonardo TerranovaRespiratory Unit, Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.ORCID 0000-0003-3596-104X
Roberto Carlos Castrejón-PérezInstituto Nacional de Geriatría, National Institutes of Health, Ministry of Health, Ciudad de México 14080, Mexico.ORCID 0000-0001-6081-9243
Franklin Garcia-GodoyBioscience Research Center, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0001-8133-3306
Tiziano LucchiGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.ORCID 0000-0002-2029-5120
Pier Carmine PassarelliDepartment of Head and Neck and Sensory Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS, University Cattolica del Sacro Cuore, 00168 Rome, Italy.

Funding

Italian Ministry of Health Ricerca Corrente
6 · The paper itself

Abstract

The oral-gut microbiota axis is a relatively new field of research. Although most studies have focused separately on the oral and gut microbiota, emerging evidence has highlighted that the two microbiota are interconnected and may influence each other through various mechanisms shaping systemic health. The aim of this review is therefore to provide an overview of the interactions between oral and gut microbiota, and the influence of diet and related metabolites on this axis. Pathogenic oral bacteria, such as

Indexed as

Gastrointestinal MicrobiomeLongevityMouthBile Acids and SaltsDietDysbiosisHumansBile Acids and Saltsdietgut dysbiosisgut microbiotainflammationmicrobiomeoral microbiotaprebioticsprobioticssystemic diseases

Identifiers

PMID40806122
PMCPMC12349001

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.