Evidence map›Paper›PMID 40806120›Full record

ArticleNutrients2025

Low Dietary Folate Increases Developmental Delays in the Litters of

Karen E Christensen, Marie-Lou Faquette, Vafa Keser, Alaina M Reagan, Aaron T Gebert, Teodoro Bottiglieri, Gareth R Howell, Rima Rozen

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karen E ChristensenDepartments of Human Genetics and Pediatrics, McGill University, Montreal, QC H3A 0C7, Canada.ORCID 0000-0003-1741-0375
Marie-Lou FaquetteDepartments of Human Genetics and Pediatrics, McGill University, Montreal, QC H3A 0C7, Canada.ORCID 0000-0001-7179-933X
Vafa KeserDepartments of Human Genetics and Pediatrics, McGill University, Montreal, QC H3A 0C7, Canada.
Alaina M ReaganThe Jackson Laboratory, Bar Harbor, ME 04609, USA.
Aaron T GebertCenter of Metabolomics, Institute of Metabolic Disease, Baylor Scott and White Research Institute, Dallas, TX 75204, USA.
Teodoro BottiglieriCenter of Metabolomics, Institute of Metabolic Disease, Baylor Scott and White Research Institute, Dallas, TX 75204, USA.ORCID 0000-0002-4199-7551
Gareth R HowellThe Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0003-0565-6474
Rima RozenDepartments of Human Genetics and Pediatrics, McGill University, Montreal, QC H3A 0C7, Canada.

Funding

CIHR PJT-173521
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Developmental DisabilitiesEmbryonic DevelopmentFolic AcidFolic Acid DeficiencyMethylenetetrahydrofolate Reductase (NADPH2)AnimalsDietFemaleGenotypeHomocysteineLiverMaternal Nutritional Physiological PhenomenaMiceMice, Inbred BALB CPregnancyTetrahydrofolates5-methyltetrahydrofolateFolic AcidHomocysteineMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, mouseTetrahydrofolatesdevelopmental defectsdevelopmental delayembryofolate deficiencyhomocysteinemethyltetrahydrofolateMTHFR

Identifiers

PMID40806120
PMCPMC12348234

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.