Evidence map›Paper›PMID 40806073›Full record

ArticleNutrients2025

Curcumin-Rich Curry Consumption Is Associated with Lower Risk of Cognitive Decline and Incidence of Mild Cognitive Impairment or Dementia: An Asian Population-Based Study.

Yanxia Lu, Tih Shih Lee, Wee Shiong Lim, Philip Yap, Chin Yee Cheong, Iris Rawtaer, Tau Ming Liew, Xinyi Gwee, Qi Gao, Keng Bee Yap and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects ofFrontiers in nutrition · 2026
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yanxia LuDepartment of Medical Psychology and Ethics, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0003-0878-7525
Tih Shih LeeNeuroscience and Behavioral Disorders Program, Duke-NUS Medical School, Singapore 169857, Singapore.
Wee Shiong LimInstitute of Geriatrics and Active Aging, Department of Geriatric Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.ORCID 0000-0003-3975-7230
Philip YapDepartment of Geriatric Medicine, Khoo Teck Puat Hospital, Singapore 768828, Singapore.ORCID 0000-0001-9465-5937
Chin Yee CheongDepartment of Geriatric Medicine, Khoo Teck Puat Hospital, Singapore 768828, Singapore.
Iris RawtaerDepartment of Psychiatry, Sengkang General Hospital, Singapore 544886, Singapore.
Tau Ming LiewDepartment of Psychiatry, Singapore General Hospital, Singapore 169608, Singapore.ORCID 0000-0003-1555-7752
Xinyi GweeGerontological Research Programme (GRP), Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119074, Singapore.
Qi GaoDepartment of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Keng Bee YapDepartment of Medicine, Ng Teng Fong General Hospital, Singapore 609606, Singapore.
Tze Pin NgDepartment of Geriatric Medicine, Khoo Teck Puat Hospital, Singapore 768828, Singapore.

Funding

Biomedical Research Council BMRC/08/1/21/19/567National Medical Research Council NMRC/1108/2007National Medical Research Council NMRC/CIRG/1409/2014
6 · The paper itself

Abstract

BACKGROUND/

objectivesWe studied the possible protective effect of dietary curcumin in curry meals against cognitive decline and mild cognitive impairment (MCI) and dementia in a population-based Singapore Longitudinal Ageing cohort study.

methodsBaseline curry consumption frequency was categorized as five categories ranging from 'never or rarely' to 'daily'. Among 2920 participants (mean age 65.5 ± SD 7.1 years) free of stroke, Parkinson's disease, or traumatic brain injury at baseline, cognitive decline (MMSE drop ≥2) was assessed at 3-5 years (mean 4.5) follow-up. Occurrence of incident MCI-dementia was assessed at follow-up among 2446 participants without neurocognitive disorder at baseline.

resultsA decreasing linear trend was observed between higher levels of curry consumption and cognitive decline (

conclusionsThe intake of dietary curcumin through curry shows a dose-dependent reduction in incidence of cognitive decline and MCI-dementia in this Asian population of community-based elders.

Indexed as

Cognitive DysfunctionCurcuminDementiaDietAgedAsian PeopleFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedRisk FactorsSingaporeCurcumincurcumincurryneurocognitive disorderpopulation-based study

Identifiers

PMID40806073
PMCPMC12348642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.