Evidence map›Paper›PMID 40805228›Full record

ArticleCancers2025

Efficient Implementation of a Robot-Assisted Radical Cystectomy Program in a Naïve Centre Experienced in Open Radical Cystectomy and Other Robot-Assisted Surgeries: A Comparative Analysis of Perioperative Outcomes and Complications.

Gianluca Giannarini, Gioacchino De Giorgi, Maria Abbinante, Carmine Franzese, Jeanlou Collavino, Fabio Traunero, Marco Buttazzi, Antonio Amodeo, Angelo Porreca, Alessandro Crestani

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gianluca GiannariniUrology Unit, Santa Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.ORCID 0000-0002-6995-246X
Gioacchino De GiorgiUrology Unit, Santa Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.
Maria AbbinanteUrology Unit, Santa Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.
Carmine FranzeseUrology Unit, Santa Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.
Jeanlou CollavinoUrology Unit, Santa Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.
Fabio TrauneroUrology Unit, Santa Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.ORCID 0000-0002-3272-528X
Marco ButtazziDepartment of Medicine, University of Udine, 33100 Udine, Italy.
Antonio AmodeoOncological Urology Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.ORCID 0009-0009-2730-0402
Angelo PorrecaUrology Unit, Humanitas Gavazzeni, 24125 Bergamo, Italy.
Alessandro CrestaniUrology Unit, Santa Maria della Misericordia University Hospital, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy.ORCID 0000-0001-7443-8740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesWhile robot-assisted radical cystectomy (RARC) has shown potential benefits over open radical cystectomy (ORC), such as reduced blood loss and quicker recovery, its adoption has been limited because of its complexity and long learning curve, especially for urinary diversion. We assessed whether a RARC program with fully intracorporeal urinary diversion could be safely implemented in a hospital with no prior experience in RARC, but with expertise in ORC and other robotic surgeries. We also compared perioperative outcomes and complications between RARC and ORC during the implementation phase.

methodsThis retrospective comparative study included 50 consecutive patients who underwent RARC between June 2023 and January 2025 and 50 patients previously treated with ORC. All RARC cases were performed with intracorporeal urinary diversion. A structured proctoring program guided two surgeons through a stepwise training approach by an expert RARC surgeon. Perioperative outcomes and 90-day complications were compared.

resultsAll RARC procedures were completed fully intracorporeally with no conversions to open surgery. Compared with ORC, RARC was associated with significantly shorter operative times (for ileal conduit diversion) and hospital stays, lower estimated blood loss, and fewer postoperative complications. There were no differences in intraoperative complications. Worst single grade ≥ 3 complications were significantly less frequent in the RARC than the ORC group (11 [11%] versus 21 [21%],

conclusionsA RARC program can be safely and effectively implemented in a previously RARC-naïve centre with existing surgical expertise. The robotic approach offers clear perioperative benefits and may represent a favourable alternative to open surgery.

Indexed as

bladder cancercomplicationscutaneous ureterostomyeducationileal conduitlearning curveminimally invasive surgerymorbidityradical cystectomyrobot-assisted surgerytrainingurinary diversion

Identifiers

PMID40805228
PMCPMC12345945

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.