Evidence map›Paper›PMID 40805227›Full record

ArticleCancers2025

Survival in Patients with Colorectal Cancer and Isolated Brain Metastases: Temporal Trends and Prognostic Factors from the National Cancer Database (2010-2020).

Zouina Sarfraz, Diya Jayram, Ahmad Ozair, Lydia Hodgson, Shreyas Bellur, Arun Maharaj, Vyshak A Venur, Sarbajit Mukherjee, Manmeet S Ahluwalia

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. IRS2 as a driver and therapeutic target in brain metastases from colorectal cancer: a systematic review of mechanistic and translational evidence.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zouina SarfrazMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.ORCID 0000-0002-5132-7455
Diya JayramMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.
Ahmad OzairMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.ORCID 0000-0001-6570-4541
Lydia HodgsonMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.
Shreyas BellurMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.
Arun MaharajMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.ORCID 0000-0003-1698-6997
Vyshak A VenurDivision of Medical Oncology, Department of Medicine, University of Washington, Seattle Cancer Care Alliance and Fred Hutchinson Cancer Research Center, Seattle, WA 98195, USA.
Sarbajit MukherjeeMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.
Manmeet S AhluwaliaMiami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.ORCID 0000-0003-3794-9511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain metastasescolorectal cancerhealthcare inequitiesoverall survivalprognostic factorsstereotactic radiosurgerysystemic therapytreatment modalities

Identifiers

PMID40805227
PMCPMC12345898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.