Evidence map›Paper›PMID 40804998›Full record

ArticleAnimals : an open access journal from MDPI2025

Characterisation of the Faecal Microbiota in Dogs with Mast Cell Tumours Compared with Healthy Dogs.

Catarina Aluai-Cunha, Diana Oliveira, Hugo Gregório, Gonçalo Petrucci, Alexandra Correia, Cláudia Serra, Andreia Santos

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Catarina Aluai-CunhaDepartment of Veterinary Clinics, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, R. Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-7572-6389
Diana OliveiraDepartment of Veterinary Clinics, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, R. Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
Hugo GregórioAnicura CHV-Veterinary Hospital Center, R. Manuel Pinto de Azevedo 118, 4100-320 Porto, Portugal.
Gonçalo PetrucciAnimal and Veterinary Department, University Institute of Health Sciences, IUCS-CESPU, Rua Central de Gandra, 1317, 4585-166 Gandra PRD, Portugal.ORCID 0000-0003-1751-2419
Alexandra CorreiaInstitute for Research and Innovation in Health (I3S), University of Porto, R. Alfredo Allen 208, 4200-135 Porto, Portugal.ORCID 0000-0003-0408-6262
Cláudia SerraInterdisciplinary Centre of Marine and Environmental Research (CIMAR/CIIMAR), Av. General Norton de Matos S/N, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-9852-2426
Andreia SantosDepartment of Veterinary Clinics, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, R. Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-7888-1739

Funding

CIIMAR Strategic Funding UIDB/04423/2020CIIMAR Strategic Funding UIDP/04423/2020Fundação para a Ciência e Tecnologia 2021.08598.BDFundação para a Ciência e Tecnologia 2022.07006.CEECINDRESOLVE Health 2.0 Innovation Acceleration Pro-407 gram - "Microbiome in Agro-Food & Health Biotech Living Lab" - financed by FEDER Thematic 408 Operational Program Competitiveness and Internationalization POCI-01-0246-FEDER-181287
6 · The paper itself

Abstract

Mast cell tumours (MCT) are the most common cutaneous neoplasms in dogs, with variable behaviours and patient survival time. Both indolent and aggressive forms have been described, but much remains to be explored regarding prognosis and therapy. Evidence has highlighted the influence of microbiota on multiple health and disease processes, including certain types of cancer in humans. However, knowledge remains scarce regarding microbiota biology and its interactions in both humans and canine cancer patients. This study aimed to characterise the faecal microbiota of dogs with MCT and compare it with that of healthy individuals. Twenty-eight dogs diagnosed with MCT and twenty-eight healthy dogs were enrolled in the study. Faecal samples were collected and analysed by Illumina sequencing of 16S rRNA genes. Alpha diversity was significantly lower in dogs with cancer, and the species diversity InvSimpson Indexwas reduced (

Indexed as

dogdysbiosismast cell tumoursmicrobiota

Identifiers

PMID40804998
PMCPMC12345436

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.