Evidence map›Paper›PMID 40804960›Full record

ArticleAnimals : an open access journal from MDPI2025

Serum Trimethylamine N-Oxide as a Diagnostic and Prognostic Biomarker in Dogs with Chronic Kidney Disease: A Pilot Study.

Seung-Ju Kang, Wan-Gyu Kim, Keon Kim, Chang-Hyeon Choi, Jong-Hwan Park, Seog-Jin Kang, Chang-Min Lee, Yoon Jung Do, Woong-Bin Ro

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seung-Ju KangCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0009-0003-3065-6692
Wan-Gyu KimCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.
Keon KimCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0002-8759-7764
Chang-Hyeon ChoiCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0009-0003-9529-1313
Jong-Hwan ParkCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.
Seog-Jin KangAnimal Diseases & Health Division, National Institute of Animal Science, Rural Development Administration, Wanju-gun 55365, Republic of Korea.ORCID 0000-0001-7838-9042
Chang-Min LeeCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0002-7867-1053
Yoon Jung DoAnimal Diseases & Health Division, National Institute of Animal Science, Rural Development Administration, Wanju-gun 55365, Republic of Korea.ORCID 0000-0003-3207-3514
Woong-Bin RoCollege of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0001-7123-8436

Funding

This work was carried out with the support of "Cooperative Research Program for Agriculture Science and Technology Development (Project No. RS-2023-00232301)" Rural Development Ad-ministration, Republic of Korea. RS-2023-00232301
6 · The paper itself

Abstract

Trimethylamine N-oxide (TMAO) is known to increase in human cardiovascular, metabolic, and renal diseases. In human medicine, TMAO has recently been utilized as a diagnostic and prognostic biomarker for renal dysfunction, and research is ongoing regarding its potential as a therapeutic target. This study aimed to evaluate the diagnostic and prognostic potential of TMAO as a supportive biomarker in dogs with chronic kidney disease (CKD). To assess its diagnostic utility, TMAO concentrations were compared between a CKD group (

Indexed as

chronic kidney diseasedogstrimethyl-amine N-oxide

Identifiers

PMID40804960
PMCPMC12345525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.