Evidence map›Paper›PMID 40804938›Full record

ArticleDiagnostics (Basel, Switzerland)2025

HMGB1 Deficiency Occurs in a Broad Range of Human Cancers and Is Often Associated with Unfavorable Tumor Phenotype.

Viktoria Chirico, Hena Sharifi, Maria Christina Tsourlakis, Seyma Büyücek, Clara Marie von Bargen, Katharina Möller, Florian Lutz, David Dum, Martina Kluth, Claudia Hube-Magg and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Viktoria ChiricoInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Hena SharifiInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Maria Christina TsourlakisInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Seyma BüyücekInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-9106-6595
Clara Marie von BargenInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Katharina MöllerInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Florian LutzInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
David DumInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-7884-4313
Martina KluthInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Claudia Hube-MaggInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-7542-4340
Georgia Makrypidi-FrauneInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Piero CaneveInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Maximilian LennartzInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-1572-8200
Morton FreytagInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0009-0001-3841-444X
Sebastian Dwertmann RicoInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Simon KindInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Viktor ReiswichInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Eike BurandtInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Till S ClauditzInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-4257-856X
Patrick LebokInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-3652-532X
Christoph FrauneInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Till KrechInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Sarah MinnerInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Andreas H MarxDepartment of Pathology, Academic Hospital Fürth, 90766 Fürth, Germany.
Waldemar WilczakInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Ronald SimonInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0003-0158-4258
Guido SauterInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-9024-4978
Stefan SteurerInstitute of Pathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Kristina JansenGeneral, Visceral and Thoracic Surgery Department and Clinic, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HMGB1 deficiencyhuman cancersimmunohistochemistrytissue microarraytumor phenotype

Identifiers

PMID40804938
PMCPMC12346012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.