Evidence map›Paper›PMID 40804865›Full record

ArticleDiagnostics (Basel, Switzerland)2025

A Rare t(3;15;17) in a Patient with Acute Promyelocytic Leukemia: Case Report and Review of the Literature.

Linda Shi, Chu En Chen, Tahmeena Ahmed, Jacob Rocha, Pons Materum, Sashank Cherukuri, Leah Gallagher, Paula Fernicola, Roxana Ponce, Htien Lee and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Linda ShiThe International Circle of Genetics Studies Project, New York Chapter, 25 Pinnacle Dr., New York, NY 11777, USA.
Chu En ChenThe International Circle of Genetics Studies Project, New York Chapter, 25 Pinnacle Dr., New York, NY 11777, USA.
Tahmeena AhmedRenaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Jacob RochaThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Pons MaterumThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.ORCID 0000-0003-0102-383X
Sashank CherukuriDepartment of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Leah GallagherThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Paula FernicolaThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Roxana PonceThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Htien LeeThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Christina GiordanoThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Gabriela EvansThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Changtai TianThe Cytogenetics Lab at the Department of Pathology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Carlos A TiradoThe International Circle of Genetics Studies Project, New York Chapter, 25 Pinnacle Dr., New York, NY 11777, USA.ORCID 0000-0002-5339-5347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a 48-year-old female with a past medical history of endometrioid adenocarcinoma who presented with symptoms of spontaneous gum bleeding, post-coital bleeding, and upper extremities-lower extremities-abdomen ecchymosis. Initial laboratory findings were significant for cytopenia and disseminated intravascular coagulation (DIC). Due to a suspected case of acute promyelocytic leukemia (APL), conventional karyotyping and fluorescence in situ hybridization (FISH) were performed. FISH analysis confirmed an unusual chromosome rearrangement that affected chromosomes 3, 15, and 17. This t(3;15;17)(q29;q24;q21) was characterized by the presence of

Indexed as

acute promyelocytic leukemiaatypical karyotypecytogeneticsPML::RARA

Identifiers

PMID40804865
PMCPMC12345950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.