Evidence map›Paper›PMID 40804769›Full record

ArticleJournal of cataract and refractive surgery2026

Capsulotomy morphology in cataract surgery: comparison of five femtosecond lasers.

Isabel A Joia, Jonas M Dürmüller, Willi Halfter, Carsten H Meyer, Paul Bernhard Henrich

Abstract readComparative Study
In one paragraph

Article in Journal of cataract and refractive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Isabel A JoiaFrom the University of Basel, Basel, Switzerland (Joia); Università della Svizzera Italiana, Lugano, Switzerland (Dürmüller, Henrich); Department of Ophthalmology, University of Basel, Basel, Switzerland (Halfter); Augenzentrum Grischun, Davos, Switzerland (Meyer); Department of Ophthalmology, University of Marburg, Germany (Meyer); Oftacentro, Lugano, Switzerland (Henrich).ORCID 0009-0000-6241-7467
Jonas M DürmüllerORCID 0000-0003-0965-8135
Willi Halfter
Paul Bernhard HenrichORCID 0000-0002-0578-0312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the capsulotomy rim morphology of anterior lens capsules obtained by 5 femtosecond laser-assisted cataract surgery (FLACS) platforms: Catalys, FEMTO LDV Z8, LensAR, LenSx, and Victus.

settingUniversity of Basel, Basel, Switzerland.

designExperimental study.

methodsAnterior lens capsules from 6 interventions per laser platform were collected (N = 30). 4 of each were assessed under light microscopy (LM; n = 20), and 2 were assessed under scanning electron microscopy (n = 10). A qualitative evaluation of all samples was conducted, as well as a semiquantitative analysis of the extent of irregularities present in LM samples. The Dunn multiple comparisons test was conducted to determine which lasers produced significantly smoother capsulotomies.

resultsIrregularities along the lens capsule rim were observed in all samples. Distinct irregularities were observed for Catalys (unconnected laser pulses bordering the capsulotomy), FEMTO LDV Z8 (numerous additional rows of laser pulses), and LensAR (at least one section with multiple rows of laser pulses). Victus demonstrated a significantly higher degree of smoothness of capsulotomy (median = 306 degrees) compared with Catalys (median = 171 degrees) ( P = .02). The medians for other laser platforms fell between these values.

conclusionsDifferent laser platforms produce morphologically and quantitatively distinct irregularities, which may influence capsulotomy strength differently. FEMTO LDV Z8, a low-energy laser, did not produce a smoother capsulotomy than the high-energy lasers. Our results suggest that, with current technologies, the precision of the laser is more important than the pulse energy in determining the regularity of the capsulotomy surface.

Indexed as

Anterior Capsule of the LensCataract ExtractionLaser TherapyCapsulorhexisHumansMicroscopy, Electron, Scanning

Identifiers

PMID40804769
PMCPMC12777582

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