ArticleBMC neurology2025
Heterogeneous hematoma density predicts poor outcome in patients with supratentorial intracerebral hemorrhage after craniotomy.
Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
BACKGROUND AND
objectiveThe density of hematoma is an imaging marker that has been used to predict hematoma expansion (HE) in patients with supratentorial intracerebral hemorrhage (SICH). However, its relationship with postoperative rebleeding and outcomes in surgical patients remains unclear. This study aimed to evaluate the impact of hematoma density on postoperative rebleeding and outcomes in patients with spontaneous supratentorial ICH after craniotomy.
methodsThis retrospective study included 331 patients with spontaneous SICH who underwent craniotomy at the affiliated Jinyang Hospital of Guizhou Medical University, between January 2019 and October 2023. Hematoma density was classified as heterogeneous if there were ≥ 3 low-density lesions within the ICH. The primary outcome measure was major disability, defined as a modified Rankin Scale score of 4-6. Patients were divided into homogeneous (n = 182) and heterogeneous (n = 149) groups based on computed tomography (CT) features at admission. A multivariate logistic regression model was used to analyze the independent correlation between hematoma density and postoperative rebleeding and poor outcomes.
resultsAt 30 days and 6 months after craniotomy, among the 149 patients with heterogeneous density, 95 (63.8%) and 79 (53.0%) patients had a poor outcome, respectively. In contrast, among the 182 patients with homogeneous density, 74 (40.7%) and 61 (33.5%) had poor outcomes. Multivariate logistic regression analysis demonstrated that heterogeneous density independently predicts poor outcomes at 30 days (odds ratio 2.354; 95% confidence interval [1.446-3.833]; P<0.001) and 6 months (odds ratio 2.039; 95% confidence interval [1.268-3.279]; P=0.003) in patients with ICH after craniotomy but not rebleeding after craniotomy.
conclusionsHeterogeneous hematoma density predicts poor outcomes at 30 days and 6 months in patients with spontaneous supratentorial ICH after craniotomy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.