Evidence map›Paper›PMID 40804656›Full record

ArticleBMC infectious diseases2025

Identifying malaria epidemic periods in Togo by health district and target group: a generalised additive model approach.

Anne Thomas, Tchaa A Bakai, Tinah Atcha-Oubou, Tchassama Tchadjobo, René Ecochard, Muriel Rabilloud, Nicolas Voirin

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Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Anne ThomasUniversité de Lyon, Lyon, France. thomas.anne10@hotmail.fr.
Tchaa A BakaiUniversité de Lyon, Lyon, France.
Tinah Atcha-OubouProgramme National de Lutte contre le Paludisme (PNLP), Lomé, Togo.
Tchassama TchadjoboProgramme National de Lutte contre le Paludisme (PNLP), Lomé, Togo.
René EcochardUniversité de Lyon, Lyon, France.
Muriel RabilloudUniversité de Lyon, Lyon, France.
Nicolas VoirinEpidemiology and Modelling of Infectious Diseases (EPIMOD), Lent, France.

Funding

Association Nationale de la Recherche et de la Technologie 2017/1805
6 · The paper itself

Abstract

backgroundInformation on seasonal malaria transmission is required for the development of targeted intervention programmes in malaria-endemic countries. This study aimed to determine the epidemic periods of malaria by health district and target group in Togo.

methodsMonthly data of confirmed malaria cases from 2013 to 2017 were analysed in this study. Data were routinely collected by the Togo National Malaria Control Programme (NMCP). They were aggregated by health district and target group (children < 5 years old, children ≥ 5 years old and adults, and pregnant women). Estimates of excess malaria cases compared to January were obtained through generalised additive models. The number of epidemic periods, the number of months with an excess of cases, the months with an excess of cases, the relative percentage increase of cases in the first month with an excess of cases, and the maximum relative percentage increase of cases and the corresponding month were described for each health district and target group.

resultsA total of 5,522,650 confirmed malaria cases were reported from 2013 to 2017 in Togo. Children < 5 years old, children ≥ 5 years old and adults, and pregnant women represented 36.6%, 58.5% and 4.9% of the confirmed malaria cases, respectively. A time lag of at least one month was generally observed between the onset of precipitation and the start of the epidemic periods in all three target groups. In the health districts of the Savanes region, the epidemic periods started later in the year and had a greater relative increase in malaria cases compared to January than in the health districts of the other regions. In contrast, in the health districts of the Maritime and Lome-commune regions, the epidemic periods were generally short or undetectable.

conclusionsThis study suggests that malaria control interventions should be tailored to local transmission, considering the onset and duration of epidemic periods at the district level. These results can be used to adapt the distribution of seasonal malaria chemoprevention in children < 5 years old, and then used for malaria risk stratification in addition to other data.

Indexed as

Epidemiological ModelsMalariaAdolescentAdultChildChild, PreschoolEpidemicsFemaleHumansInfantPregnancyPregnancy Complications, ParasiticSeasonsTogoYoung AdultGeneralised additive modelMalariaRoutine health information dataSeasonal epidemicsTogo

Identifiers

PMID40804656
PMCPMC12344937

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