Evidence map›Paper›PMID 40804527›Full record

ArticleNature2025

Elementary 3D organization of active and silenced E. coli genome.

Alexey A Gavrilov, Ilya Shamovsky, Irina Zhegalova, Sergey Proshkin, Yosef Shamovsky, Grigory Evko, Vitaly Epshtein, Aviram Rasouly, Anna Blavatnik, Sudipta Lahiri and 3 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Characterizing the Impact of Nucleoid-Associated Proteins on HU-DNA Interactions by Live-Cell Single-Molecule Tracking.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Prokaryotic homeostasis - a solution to thrive and survive.Frontiers in molecular biosciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexey A Gavrilov *Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Ilya Shamovsky *Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.
Irina ZhegalovaInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0002-3556-1639
Sergey ProshkinEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Yosef ShamovskyDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.
Grigory EvkoInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0001-8566-6204
Vitaly EpshteinDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.
Aviram RasoulyDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0003-2857-6151
Anna BlavatnikDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.
Sudipta LahiriDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.
Eli RothenbergDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-1382-1380
Sergey V RazinInstitute of Gene Biology, Russian Academy of Sciences, Moscow, Russia. sergey.v.razin@gmail.com.
Evgeny NudlerDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA. evgeny.nudler@nyulangone.org.ORCID 0000-0002-8811-3071

Funding

Mechanisms of Human DNA Double-Strand Break Repair via Quantitative Single-Molecule Imaging - Equipment SupplementR35GM134947 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Eli Rothenberg · 2020 to 2026
$3.4M
NIGMS NIH HHS R35 GM134947
6 · The paper itself

Abstract

Unravelling how genomes are spatially organized and how their three-dimensional (3D) architecture drives cellular functions remains a major challenge in biology

Indexed as

Chromosomes, BacterialEscherichia coliGene SilencingGenome, BacterialDNA, BacterialDNA-Binding ProteinsEscherichia coli ProteinsGene Transfer, HorizontalMolecular ChaperonesNucleic Acid ConformationDNA, BacterialDNA-Binding ProteinsEscherichia coli ProteinsMolecular ChaperonesStpA protein, E coli

Identifiers

PMID40804527
PMCPMC12460168

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.