ArticleNature2025
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.
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42citing papers in PubMed
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Who cites it
42 citing papers in PubMed.
- Cell death in ischemia-reperfusion injury: beyond a single-cell-death perspective.Biomarker research · 2026Review
- Tetramethylpyrazine modulates the Nrf2/JNK axis to intervene in ferroptosis and neuroinflammation after spinal cord injury: an integrated perspective from antioxidant to regenerative therapy.Molecular biology reports · 2026Review
- CLPP loss confers sex-specific protection from renal ischemia reperfusion injury.Redox biology · 2026Article
- Mechanisms of regeneration and maladaptive repair in acute kidney injury.Nature reviews. Nephrology · 2026Review
- Ferroptotic propagation: from single-cell execution to tissue-scale death programs.Cell research · 2026Review
- Di(2-Ethylhexyl) Phthalate Exposure and Risk of Diabetic Kidney Disease: Epidemiological Association and Mechanistic Insights.Diabetes/metabolism research and reviews · 2026Article
- Ferroptosis in T cells: mechanisms, biology and translational opportunities.Nature reviews. Immunology · 2026Review
- Pre-treatment with 2-mercaptoethanol attenuates ferroptosis-associated redox imbalance and inflammatory responses, but not tubulointerstitial fibrosis, in unilateral ureteral obstruction.Pharmacological reports : PR · 2026Article
- PLA2G2F suppresses ferroptosis through phospholipid remodeling.Nature structural & molecular biology · 2026Article
- MiR-940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The nuclear receptor ESRRA is a crucial regulator of acute kidney injury through inhibition of the lipophagy-ferroptosis axis.Autophagy · 2026Article
- Selective autophagy in kidney health and disease.Nature reviews. Nephrology · 2026Review
- Insights from integrative spatial transcriptomics in sepsis-associated acute kidney injury.Nature reviews. Nephrology · 2026Review
- Remodeling of ferroptotic necroinflammation by dexamethasone in acute tubular necrosis.Cell death & disease · 2026Article
- What does not kill you makes you Weaker!Cell death and differentiation · 2026Article
- Clinical impact of genetic testing in inherited kidney diseases.Clinical kidney journal · 2026Article
- Hydropersulfides promote angiogenesis and preserve vascular function.Redox biology · 2026Article
- Clinical implications of ferroptosis in critical illness: a narrative review.Journal of intensive care · 2026Review
- Iron Biology in Acute Kidney Injury: Catalytic Iron, Hepcidin-Ferroportin Axis, and NGAL-A Narrative Review.International journal of molecular sciences · 2026Review
- Maternal PMParticle and fibre toxicology · 2026Article
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
47 authors.
Wulf Tonnus *Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.ORCID 0000-0002-9728-1413
Francesca Maremonti *Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Shubhangi Gavali *Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.ORCID 0000-0003-2876-1453
Marlena Nastassja SchlechtDivision of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.ORCID 0000-0001-8893-5326
Florian GembardtDepartment of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Alexia BelavgeniInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.ORCID 0000-0001-6311-5858
Nadja LeinungDepartment of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Karolin FladeDivision of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.ORCID 0009-0009-5449-2825
Natalie BetheDivision of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Sofia TraikovInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Anne HaagChair of Organic Chemistry, Technische Universität Dresden, Dresden, Germany.ORCID 0009-0009-5111-7413
Danny SchillingDivision of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Sider PenkovCenter of Membrane Biochemistry and Lipid Research, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Melodie MallaisDepartment of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.
Christine GailletEquipe Labellisée Ligue Contre le Cancer, Institut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0002-1208-1130
Claudia MeyerDepartment of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Melika KatebiDepartment of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Anushka RayDepartment of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Louisa M S GerhardtDepartment of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Anne BruckerDivision of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Jorunn Naila BeckerDivision of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.ORCID 0009-0004-5273-1320
Mirela TmavaDivision of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.ORCID 0009-0002-4116-3634
Lisa SchlickerDivision of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Almut SchulzeDivision of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-8199-6422
Nina HimmerkusInstitute of Physiology, Christian-Albrecht-University Kiel, Kiel, Germany.ORCID 0000-0002-2910-6728
Andrej ShevchenkoMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0002-5079-1109
Mirko PeitzschInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Uladzimir BarayeuMax Planck Institute for Polymer Research, Mainz, Germany.
Sonia NasiService of Rheumatology, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-6625-8309
Juliane PutzClinic for Urology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Kenneth S KorachLaboratories of Reproductive and Developmental Toxicology, NIEHS, National Institutes of Health, Research Triangle Park, NC, USA.ORCID 0000-0002-7765-418X
Joel NeugartenRenal Division, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
Ladan GolestanehRenal Division, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
Christian HugoDivision of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.ORCID 0000-0001-5895-3005
Jan Ulrich BeckerInstitute of Pathology, University Hospital of Cologne, Cologne, Germany.
Joel M WeinbergDivision for Nephrology, University of Michigan Medical Center, Ann Arbor, MI, USA.
Svenja LorenzInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-6856-0720
Bettina PronethInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID 0000-0002-4119-9437
Marcus ConradInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Eckhard WolfChair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich, Germany.ORCID 0000-0002-0430-9510
Bernd PlietkerChair of Organic Chemistry, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0001-8423-6173
Raphaël RodriguezEquipe Labellisée Ligue Contre le Cancer, Institut Curie, CNRS, INSERM, PSL Research University, Paris, France.ORCID 0000-0001-7668-446X
Derek A PrattDepartment of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0002-7305-745X
Tobias P DickDivision of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Maria FedorovaCenter of Membrane Biochemistry and Lipid Research, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0002-4692-3885
Stefan R BornsteinDepartment of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Andreas LinkermannDepartment of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany. andreas.linkermann@medma.uni-heidelberg.de.ORCID 0000-0001-6287-9725
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute tubular necrosis mediates acute kidney injury (AKI) and nephron loss
Indexed as
Acute Kidney InjuryEstradiolFerroptosisAnimalsEstrogen Receptor alphaFemaleHumansKidney TubulesMaleMiceMice, Inbred C57BLOvariectomyEsr1 protein, mouseEstradiolEstrogen Receptor alpha
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