Evidence map›Paper›PMID 40804501›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Could alteration in the vacuum phenomenon rather than its presence be a sign of spinal instability?

Emel Ece Özcan Ekşi, Murat Şakir Ekşi, Furkan Karakaş, Erhan Çelikoğlu

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Return to sports after lumbar disc herniation surgery: a survey of German surgeons and postoperative patient experiences.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Article
  3. Letter to the Editor concerning "Could alteration in the vacuum phenomenon rather than its presence be a sign of spinal instability?" by EE Özcan Ekşi, et al. (Eur Spine J [2025]; doi: 10.1007/s00586-025-09198-w).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emel Ece Özcan EkşiAcıbadem Bağdat Caddesi Medical Center, Istanbul, Turkey. emelece84@yahoo.com.
Murat Şakir EkşiSağlık Bilimleri Üniversitesi, Istanbul, Turkey.
Furkan KarakaşDokuz Eylül University, Izmir, Turkey.
Erhan ÇelikoğluSağlık Bilimleri Üniversitesi, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe intradiscal vacuum phenomenon (VP) has traditionally been regarded as a radiologic indicator of segmental instability. However, its direct relationship with postoperative spinal fusion outcomes and mechanical complications remains inadequately understood. This study aimed to investigate whether changes in the natural course of intradiscal and intrafacet VP influence clinical and mechanical outcomes following lumbar fusion surgery.

methodsThis retrospective cohort study included consecutive patients who underwent lumbar fusion surgery for degenerative spinal disorders at a tertiary spine center. Lumbar computed tomography scans obtained preoperatively and at the final follow-up were reviewed for the presence or absence of intradiscal and intrafacet VP. Associations between VP dynamics and mechanical complications (e.g., adjacent segment disease and pseudoarthrosis) were analyzed alongside patient-reported functional outcomes.

resultsThe appearance of new intrafacet VP and the resolution of pre-existing intrafacet VP at follow-up were significantly associated with increased rates of mechanical failure and adjacent segment disease. Mechanical failures occurred in 73.3% of patients with new-onset intrafacet VP (odds ratio [OR] = 3.552), while adjacent segment disorders were observed in 53.3% of these cases (OR = 3.513). In contrast, intradiscal VP showed no significant correlation with mechanical complications. Patients with newly developed intrafacet VP also demonstrated significantly poorer outcomes in terms of achieving the minimal clinically important difference for the Oswestry Disability Index. Furthermore, the presence of interbody fusion, as opposed to posterolateral fusion alone, was more closely associated with VP alterations and functional outcomes. The resolution of intradiscal VP-presumably due to solid interbody fusion-was linked to improved quality of life, whereas similar changes in intrafacet VP were associated with poorer outcomes. These associations remained relevant when analyzed along with participants' comorbidities.

conclusionPostoperative changes in intrafacet VP, rather than its mere presence, may serve as a more accurate indicator of mechanical complications and functional decline following lumbar fusion. These findings challenge the conventional assumption that intradiscal VP is the primary radiologic marker of instability. The results suggest that interbody fusion may offer improved outcomes in this context, although further prospective studies are warranted. These insights may assist clinicians in preoperative planning and patient counseling regarding the risks and expected postoperative course following lumbar fusion surgery.

Indexed as

Intervertebral Disc DegenerationJoint InstabilityLumbar VertebraePostoperative ComplicationsSpinal FusionAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedVacuumAdjacent segment diseaseFunctional outcomeLumbar spineMechanical complicationsSpinal fusionVacuum phenomenon

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.