Evidence map›Paper›PMID 40804385›Full record

ArticleBMC oral health2025

Efficacy comparison between dentofacial orthopedic treatment and adenotonsillectomy on children with obstructive sleep apnea and skeletal class II malocclusion: a retrospective study.

Gang Yang, Anqi Liu, Jie Pan, Yijie Zhao, Liming Yu, Liangyan Sun, Xianqin Tong, Yuanyuan Li, Yuehua Liu

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gang Yang *Department of Multidisciplinary Consultant Center, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China.
Anqi Liu *Department of Orthodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University, School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, 200011, China.
Jie PanDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China.
Yijie ZhaoDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China.
Liming YuDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China.
Liangyan SunDepartment of Multidisciplinary Consultant Center, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China.
Xianqin TongDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China.
Yuanyuan LiDepartment of Pediatric Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China. li_yuanyuan0650@fudan.edu.cn.
Yuehua LiuDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200001, China. liuyuehua@fudan.edu.cn.

Funding

Shanghai Municipal Health Commission 202340147Shanghai Municipal Hospital Development Center SHDC2020CR2043BShanghai Stomatological Hospital SHDC2023CRW016B-2023-01-KY09
6 · The paper itself

Abstract

objectiveThis study aims to evaluate the effects of dentofacial orthopedic treatment (DOT) and adenotonsillectomy (AT) in Obstructive Sleep Apnea (OSA) children with skeletal Class II malocclusion and adenotonsillar hypertrophy (ATH), focusing on changes in sleep respiratory function, anatomic and aerodynamic characteristics of upper airway (UA).

methodsIn this retrospective study, 38 OSA children (mean age: 8.42 years, 15 females and 23 males) were included consecutively. Patients were categorized into two groups: DOT group (n = 20) and AT group (n = 18). Baseline (T0) and follow-up (T1) assessments involved polysomnography and radiological examinations to evaluate improvements in sleep quality as well as changes in craniofacial morphology and UA variables. Aerodynamic parameters such as airflow velocity, airway resistance, and wall shear stress were quantified using computational fluid dynamics.

resultsIn the comparative analysis of sleep respiratory functions, there were no significant differences in apnea-hypopnea index changes between the treatment groups (DOT group: -3.72/h, AT group: -3.32/h, P = 0.600). In the DOT group, UA's volume average enlargements were observed in the nasopharynx, palatopharynx, glossopharynx, and hypopharynx by 54.5%, 41.6%, 34.0%, and 22.5%, respectively. In comparison, the AT group showed enlargements of 66.0%, 20.1%, 62.9%, and - 1.0%, respectively. In terms of UA aerodynamic characteristics, there were no significant differences between two groups.

conclusionsIn OSA children with skeletal Class II malocclusion and ATH, DOT as a non-invasive approach, has shown improvements in respiratory function comparable to AT, as evidenced by changes in the UA's anatomical and aerodynamic characteristics.

Indexed as

AdenoidectomyMalocclusion, Angle Class IISleep Apnea, ObstructiveTonsillectomyAdenoidsAirway ResistanceCephalometryChildFemaleHumansHypertrophyMalePolysomnographyRetrospective StudiesTreatment OutcomeAdenotonsillectomyChildrenComputational fluid dynamicsDentofacial orthopedic treatmentOSASkeletal class II malocclusion

Identifiers

PMID40804385
PMCPMC12351886

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.