SynthesisBMC gastroenterology2025
Global prevalence and correlation of intestinal parasitic infections in patients with colorectal cancer: a systematic review and meta-analysis.
Synthesis in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The dual role of parasites and parasite-derived products in cancer biology: a systematic review ofFrontiers in oncology · 2026Pooled it
- Prevalence and epidemiological characteristics of bovine cysticercosis (Cysticercus bovis) in cattle in Palestine: a slaughterhouse-based study (2018-2025).Veterinary research communications · 2026Article
- Azithromycin Mitigates Experimental Cryptosporidiosis-Driven Ileocecal Adenocarcinoma by Modulating Autophagy, Apoptosis, and PI3K/AKT Signaling.Biomedicines · 2026Article
- Emerging nano-immunotherapeutic strategies achieve metastatic colorectal cancer precision therapy.Journal of nanobiotechnology · 2026Review
- A hidden danger in cancer patients: intestinal parasites.Turkish journal of medical sciences · 2026Article
- Review
- Article
- The Impact of Helminths on Colorectal Cancer: From Infections to the Isolation of Biotherapeutics.Pathogens (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveColorectal cancer (CRC) is a leading cause of cancer-related deaths globally, and researchers continue to explore its underlying factors. This systematic review and meta-analysis study aimed to clarify the prevalence and potential association between intestinal parasitic infections (IPIs) and CRC.
methodsA comprehensive search was conducted across databases that contain articles in English, including PubMed, ScienceDirect, Web of Science, Scopus, and Google Scholar, to identify articles published up to October 2024 that reported on the prevalence of IPIs in CRC patients. Selected studies were screened according to inclusion and exclusion criteria. A random-effects model was used to estimate the pooled prevalence and odds ratios (ORs) for association IPIs in CRC.
resultsA total of 70 studies were included, and 46 case-control and cross-sectional studies were analyzed. The pooled prevalence of IPIs among CRC patients was determined to be 19.67% (95% CI: 14.81% to 25.02%). Furthermore, individuals with parasitic infections exhibited a significantly higher likelihood of developing CRC, with an OR of 3.61 (95% CI: 2.41-5.43).
conclusionThis study demonstrated a significantly high prevalence of parasitic infections, including both helminths and protozoa, among patients with CRC. The analysis revealed a notable association between IPIs and CRC, suggesting that these infections may contribute to the development and progression of the cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.