Evidence map›Paper›PMID 40804254›Full record

ArticleBlood cancer journal2025

Genomic and immunogenomic profiling of extramedullary acute myeloid leukemia reveals actionable clonal branching and frequent immune editing.

Clément Collignon, Tucker Hansen, Colin Hercus, Marianna B Ruzinova, Gabrielle Roth Guepin, Caroline Bonmati, Marie Thérèse Rubio, Pierre Feugier, Mélanie Gaudfrin, Hervé Sartelet and 8 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Clément CollignonDivision of Oncology - Hematologic Malignancies, Transplant and Cellular Therapy, Washington University in Saint Louis, Saint Louis, MO, USA.
Tucker HansenDivision of Dermatology, Washington University in Saint Louis, Saint Louis, MO, USA.ORCID http://orcid.org/0000-0002-3948-073X
Colin HercusNovocraft Technologies Sdn Bhd, Kuala Lumpur, Malaysia.ORCID http://orcid.org/0000-0001-8997-7130
Marianna B RuzinovaDepartment of Pathology and Immunology, Washington University in Saint Louis, Saint Louis, MO, USA.
Gabrielle Roth GuepinHematology Department, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Caroline BonmatiHematology Department, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Marie Thérèse RubioHematology Department, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.ORCID http://orcid.org/0000-0003-3732-5442
Pierre FeugierHematology Department, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Mélanie GaudfrinUMR 7365, IMoPA, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Hervé SarteletDepartment of Pathology, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Marion DivouxGenetic Department, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.ORCID http://orcid.org/0000-0002-5946-311X
Marc MullerGenetic Department, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Sharon HeathDivision of Oncology - Hematologic Malignancies, Transplant and Cellular Therapy, Washington University in Saint Louis, Saint Louis, MO, USA.
Geoffrey L UyDivision of Oncology - Hematologic Malignancies, Transplant and Cellular Therapy, Washington University in Saint Louis, Saint Louis, MO, USA.
David H SpencerDivision of Oncology - Hematologic Malignancies, Transplant and Cellular Therapy, Washington University in Saint Louis, Saint Louis, MO, USA.ORCID http://orcid.org/0000-0002-5314-3043
David Y ChenDivision of Dermatology, Washington University in Saint Louis, Saint Louis, MO, USA.ORCID http://orcid.org/0000-0002-3681-6576
Simona PagliucaHematology Department, Nancy University Hospital, Vandoeuvre-lès-Nancy, France. S.PAGLIUCA@chru-nancy.fr.
Francesca FerraroDivision of Oncology - Hematologic Malignancies, Transplant and Cellular Therapy, Washington University in Saint Louis, Saint Louis, MO, USA. ferrarof@wustl.edu.ORCID http://orcid.org/0000-0003-0098-9819

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Targeting the Bone Marrow Microenvironment In Acute Lymphocytic LeukemiaP50CA171963 · NCI · WASHINGTON UNIVERSITY · PI Daniel C Link · 2013 to 2026
$31.6M
NCI NIH HHS P30 CA091842NCI NIH HHS P50 CA171963
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40804254
PMCPMC12350805

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.