Evidence map›Paper›PMID 40804223›Full record

Trial reportObesity surgery2025

Effect of a 16-Week Exercise Program After Bariatric Surgery on Sarcopenia Parameters Based on FNIH, EWGSOP2, and EASO/ESPEN Criteria: the Results of the EXPOBAR Randomized Trial Program.

Cláudia Mendes, Manuel Carvalho, Carolina A Cabo, Jorge Bravo, Sandra Martins, Armando Raimundo

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05289219 (Effects of Physical Exercise on Sarcopenia After Bariatric Surgery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05289219 naunknown statusnot on this map

Effects of Physical Exercise on Sarcopenia After Bariatric Surgery: Protocol of a Randomized Controlled Study

TypeinterventionalSponsorUniversity of ÉvoraRan2021 to 2023Enrolled60ConditionsSarcopenic Obesity, Bariatric Surgery CandidateArmsEXPOBAR
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cláudia MendesUniversidade de Évora, Comprehensive Health Research Centre (CHRC), Évora, Portugal. klaudinha@icloud.com.
Manuel CarvalhoUniversidade de Évora, Comprehensive Health Research Centre (CHRC), Évora, Portugal.
Carolina A CaboUniversidade de Évora, Comprehensive Health Research Centre (CHRC), Évora, Portugal.
Jorge BravoUniversidade de Évora, Comprehensive Health Research Centre (CHRC), Évora, Portugal.
Sandra MartinsResearch Center in Sports Sciences, Health Sciences and Human Development, CIDESD, Vila Real, Portugal.
Armando RaimundoUniversidade de Évora, Comprehensive Health Research Centre (CHRC), Évora, Portugal.

Funding

Foundation for Science and Technology, Portugal UIDP/04923/2020
6 · The paper itself

Abstract

backgroundBariatric surgery is a recognized treatment option for severe obesity, and its effectiveness in reducing weight and controlling obesity-related conditions has been demonstrated. However, it can also lead to decreased skeletal muscle mass and strength, increasing the risk of sarcopenia after surgery. This randomized clinical trial studied the effects of a 16-week exercise program on sarcopenia in bariatric surgery patients.

methodsThirty-seven surgery candidates participated in the EXPOBAR (EXercise POst BARiatric) program and were randomized into experimental or control groups. The intervention lasted 16 weeks, starting 1 month after surgery, and included a circuit training with aerobic and resistance exercise intervention. The outcomes included physical fitness parameters (anthropometry, body composition, and physical performance) and were assessed at four time points. All participants underwent gastric bypass surgery (RYGB).

resultsThe EXPOBAR trial revealed significant and meaningful effects of the exercise intervention on anthropometric indices, such as weight (p = 0.039) and waist circumference (p = 0.010). The most substantial improvements were observed in physical function and strength metrics (p = 0.005 and p < 0.001, respectively), along with a reduction in fat mass (p = 0.006), indicating the intervention's effectiveness on sarcopenia parameters and in enhancing both physical fitness and body composition. DISCUSSION: Current findings indicate that following an initial decrease due to bariatric surgery, exercise training significantly improves functional physical capacity and strength. The exercise program in this study effectively reversed the surgery-induced loss in function and strength, reducing the number of patients at risk of sarcopenia. Physical and functional capacity are crucial noninvasive indicators for diagnosing muscle quality and sarcopenia.

conclusionLong-term management of sarcopenia and sarcopenic obesity in bariatric surgery patients requires frequent monitoring of body composition and muscle function. This approach is essential for tracking progress and optimizing treatment strategies over time. This study highlights the importance of integrating structured exercise programs into after bariatric surgery care to mitigate the risk of sarcopenia.

trial registrationThe trial was registered at Clinicaltrials.gov (NCT05289219).

Indexed as

Bariatric SurgeryCircuit-Based ExerciseExercise TherapyGastric BypassObesity, MorbidSarcopeniaAdultBody CompositionFemaleHumansMaleMiddle AgedMuscle StrengthResistance TrainingTreatment OutcomeWeight LossBariatric surgeryExerciseFat-free massSarcopeniaSkeletal muscle mass

Identifiers

PMID40804223
PMCPMC12457543

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.