Cone-beam computed tomography-guided volumetric assessment of secondary alveolar bone grafting.

Julian A Erkert, Benito K Benitez, Yoriko Lill, Sebastian Tapia Coron, Andreas A Mueller

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julian A Erkert *Oral and Craniomaxillofacial Surgery, University Hospital Basel and University of Basel, Spitalstrasse 21, Basel, 4031, Switzerland.ORCID http://orcid.org/0009-0000-0831-941X

Benito K Benitez *Oral and Craniomaxillofacial Surgery, University Hospital Basel and University of Basel, Spitalstrasse 21, Basel, 4031, Switzerland. benito.benitez@usb.ch.ORCID http://orcid.org/0000-0003-4459-6603

Yoriko LillOral and Craniomaxillofacial Surgery, University Hospital Basel and University of Basel, Spitalstrasse 21, Basel, 4031, Switzerland.ORCID http://orcid.org/0000-0003-3553-7601

Sebastian Tapia CoronOral and Craniomaxillofacial Surgery, University Hospital Basel and University of Basel, Spitalstrasse 21, Basel, 4031, Switzerland.ORCID http://orcid.org/0009-0003-5215-7851

Andreas A MuellerOral and Craniomaxillofacial Surgery, University Hospital Basel and University of Basel, Spitalstrasse 21, Basel, 4031, Switzerland.ORCID http://orcid.org/0000-0002-1973-9281

Funding

Geistlich-Stucki Foundation Cleft Maxilla ProjectResearch Foundation of the Swiss Dental Association 310-19Wellcome Trust 205008

6 · The paper itself

Abstract

This study aimed to develop and implement a standardized 3D workflow for surgical planning and outcome assessment in secondary alveolar bone grafting (SABG) using cone-beam computed tomography (CBCT). A 3D protocol was developed using medically certified software for semiautomatic segmentation, mirroring, voxel-based alignement of the maxilla and volumetric analysis of cleft and graft regions. This workflow was applied on a retrospective cohort of patients with unilateral cleft lip and alveolus (CLA) and/or cleft lip and palate (CLP) who received iliac bone mixed with synthetic biphasic calcium phosphate for bone grafting. CBCT scans (preoperative, immediate postoperative, and six-months follow-up) from 23 patients with unilateral clefts were analysed. The non-cleft side was mirrored to serve as reference for symmetric reconstruction. Measured parameters included alveolar cleft volume, grafted bone volume, integrated bone volume and missing volume. The workflow enabled reliable volumetric quantification. The preoperative cleft volume averaged 1505 mm

Indexed as

Alveolar Bone GraftingCleft LipCleft PalateCone-Beam Computed TomographyAdolescentAdultAlveolar ProcessChildFemaleHumansImaging, Three-DimensionalMaleRetrospective StudiesAlveolar bone graftingCleft lipCleft palateCone-Beam computed tomographyThree-Dimensional imaging

Identifiers

PMID40804116

DOI10.1038/s41598-025-15083-9

PMCPMC12350646

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.