Evidence map›Paper›PMID 40804051›Full record

ArticleScientific reports2025

Influence of the seasons on the chemical composition and biological properties of pistacia lentiscus L. essential oil in the mediterranean region.

Amina Labhar, Yahya El-Mernissi, Karima Ait Alla, Sanae Jahjah, Omar Benamari, Aziz Zouhri, Farah Labhar, Farhan Siddique, Chaima Alaoui Jamali, Elyoussfi Abdellah and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Alginate-Based Encapsulation ofFood science & nutrition · 2026
    Article
  4. Valorization ofPlants (Basel, Switzerland) · 2026
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Amina LabharResearch Unit in Applied Chemistry, FSTH, Abdelmalek Essaadi University, Tetouan, Morocco. amina.labhar@etu.uae.ac.ma.
Yahya El-MernissiResearch Unit in Applied Chemistry, FSTH, Abdelmalek Essaadi University, Tetouan, Morocco.
Karima Ait AllaBiology, Environment and Sustainable Development Laboratory, Higher School of Teachers (ENS), Abdelmalek Essaadi University, Tetouan, 93000, Morocco.
Sanae JahjahBiology, Environment and Sustainable Development Laboratory, Higher School of Teachers (ENS), Abdelmalek Essaadi University, Tetouan, 93000, Morocco.
Omar BenamariResearch Unit in Applied Chemistry, FSTH, Abdelmalek Essaadi University, Tetouan, Morocco.
Aziz ZouhriBioactives and Environmental Health Laboratory, Faculty of Sciences, Moulay Ismail University, B.P. 11201, Meknes, Morocco.
Farah LabharLaboratoire de Recherche en Géosciences appliqués et marines, Géotechnique et Géorisques (LR3G), Faculty of Science, Abdelmalek Essaadi University, Tetouan, Morocco.
Farhan SiddiqueDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Chaima Alaoui JamaliBiology, Environment and Sustainable Development Laboratory, Higher School of Teachers (ENS), Abdelmalek Essaadi University, Tetouan, 93000, Morocco.
Elyoussfi AbdellahResearch Unit in Applied Chemistry, FSTH, Abdelmalek Essaadi University, Tetouan, Morocco.
Amin SalhiResearch Unit in Applied Chemistry, FSTH, Abdelmalek Essaadi University, Tetouan, Morocco.
Mhamed AhariResearch Unit in Applied Chemistry, FSTH, Abdelmalek Essaadi University, Tetouan, Morocco.
Amira MetouekelUniversity of Technology of Compiègne, Compiègne Cedex, 4297 TIMR, 60205, EA, France.
Ahmad Mohammad SalamatullahDepartment of Food Science & Nutrition, College of Food and Agricultural Sciences, King Saud University, P.O. Box 2460, Riyadh, 11451, Saudi Arabia. asalamh@ksu.edu.sa.
Atrsaw Asrat MengistieDepartment of Biology, Bahir Dar University, P.O.Box 79, Bahir Dar, Ethiopia. Atrsawresearcher@gmail.com.
Hassan AmhamdiResearch Unit in Applied Chemistry, FSTH, Abdelmalek Essaadi University, Tetouan, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicinal plants are effective in treating many infections. Pistacia lentiscus L., whose oil is recognized for its biological properties, is attracting growing interest in medical research. These biological properties are due to their chemical composition (CC), which various conditions, like climate, can affect. P. lentiscus EOs biological properties from December, May, and August were investigated in vitro; gas chromatography-mass spectrometry (GC-MS) helped analyse their CC. Autodock Vina was used for molecular docking and SwissADME was used for ADMET analysis. The Eos of P. lentiscus leaves collected in December showed a remarkable presence of β-caryophyllene and β-myrcene. May Eos, α-pinene dominated, while August Eos, β-pinene, and D-limonene were predominant. The biological activity of Eos from P. lentiscus collected in August was highest compared to other periods. During this time (August), the leave's Eos showed significant antibacterial, antioxidant, and anti-inflammatory activity. The computational molecular docking and ADMET results align with experimental evidence, lending scientific validation to the traditional medicinal uses of the plants from which these compounds were derived. These results provide valuable information on the seasonal dynamics of the CC of P. lentiscus Eos and underline the importance of taking environmental factors into account in studies of metabolite biosynthesis.

Indexed as

Oils, VolatilePistaciaSeasonsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsBicyclic MonoterpenesGas Chromatography-Mass SpectrometryMediterranean RegionMolecular Docking SimulationPlant LeavesPolycyclic SesquiterpenesAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsBicyclic MonoterpenescaryophylleneOils, VolatilePolycyclic Sesquiterpenes

Identifiers

PMID40804051
PMCPMC12350941

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.