Evidence map›Paper›PMID 40803858›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Safe Childbirth in a Patient with Neuromyelitis Optica Spectrum Disorder Treated with Satralizumab.

Hiroshi Yaguchi, Shinji Miyagawa, Ryoji Nakada, Sumire Yamamoto, Ryouta Goto, Satoru Funaki

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroshi YaguchiDepartment of Neurology, The Jikei University Kashiwa Hospital, Japan.
Shinji MiyagawaDepartment of Neurology, The Jikei University Kashiwa Hospital, Japan.
Ryoji NakadaDepartment of Neurology, The Jikei University Kashiwa Hospital, Japan.
Sumire YamamotoDepartment of Neurology, The Jikei University Kashiwa Hospital, Japan.
Ryouta GotoDepartment of Obstetrics and Gynecology, The Jikei University Kashiwa Hospital, Japan.
Satoru FunakiDepartment of Obstetrics and Gynecology, The Jikei University Kashiwa Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 30-year-old woman presented with optic neuritis. On an examination, aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder (NMOSD) was diagnosed. Following immunotherapy for the NMOSD attack, prednisolone 20 mg was prescribed as maintenance therapy to prevent further relapse. Although the attacks recurred six times before and after her first delivery, none occurred after the addition of satralizumab. She became pregnant again at 41 years old and gave birth safely. No attacks occurred with prednisolone 10 mg and satralizumab. The concentration of satralizumab in the umbilical cord blood was approximately half that in the maternal serum, but the infant developed well with no malformations.

Indexed as

Neuromyelitis OpticaParturitionAdultAquaporin 4FemaleHumansInfant, NewbornPrednisolonePregnancyPregnancy ComplicationsAquaporin 4Prednisolonebreast feedingchildbirthneuromyelitis optica spectrum disorderpregnancysatralizumab

Identifiers

PMID40803858
PMCPMC13070572

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.