Evidence map›Paper›PMID 40803848›Full record

ReviewInternal medicine (Tokyo, Japan)2026

Splenic Infarction Associated with Sickle Cell Trait: A Diagnosis Based on a Characteristic History of Climbing Mt. Fuji, with a Brief Literature Review.

Daisuke Haratake, Daisuke Miyamori, Kotaro Ikeda, Yuya Shigenobu, Shuhei Yoshida, Masanori Ito

Abstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daisuke HaratakeDepartment of General Internal Medicine, Hiroshima University Hospital, Japan.
Daisuke MiyamoriDepartment of General Internal Medicine, Hiroshima University Hospital, Japan.
Kotaro IkedaDepartment of General Internal Medicine, Hiroshima University Hospital, Japan.
Yuya ShigenobuDepartment of General Internal Medicine, Hiroshima University Hospital, Japan.
Shuhei YoshidaDepartment of General Internal Medicine, Hiroshima University Hospital, Japan.
Masanori ItoDepartment of General Internal Medicine, Hiroshima University Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell trait (SCT) is typically asymptomatic, but high-altitude exposure and intense exertion can trigger complications, such as splenic infarction. We herein report the case of a 24-year-old African-American man of Haitian descent who developed flank pain after climbing Mt. Fuji. Contrast-enhanced computed tomography revealed splenic infarction, and an anaerobic blood culture test demonstrated sickled red blood cells. High-performance liquid chromatography confirmed SCT. Of the 13 reported cases in Japan, 92.3% occurred on Mt. Fuji, and all involved foreigners, underscoring the risk posed by rapid ascent and hypoxia. Greater awareness, screening, and education are crucial for preventing these high-altitude complications.

Indexed as

AltitudeMountaineeringSickle Cell TraitSplenic InfarctionHumansMaleYoung Adultanaerobic blood cultureMt. Fujisickle cell traitsplenic infarction

Identifiers

PMID40803848
PMCPMC13019000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.