Evidence map›Paper›PMID 40803846›Full record

ReviewInternal medicine (Tokyo, Japan)2026

Graves' Disease Diagnosed during an Evaluation of an Abnormal Opacity on a Chest X-ray with a Review of the Pertinent Literature.

Nobuhiro Kajihara, Takafumi Senokuchi, Sarie Maeda, Satoko Hanatani, Kaoru Ono, Motoyuki Igata, Naoto Kubota

Abstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nobuhiro KajiharaCenter for Metabolic Regulation of Healthy Aging, Faculty of Life Sciences, Kumamoto University, Japan.
Takafumi SenokuchiDepartment of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Japan.
Sarie MaedaDepartment of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Japan.
Satoko HanataniDepartment of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Japan.
Kaoru OnoDepartment of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Japan.
Motoyuki IgataDepartment of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Japan.
Naoto KubotaDepartment of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We treated a 43-year-old woman with Graves' disease (GD), complicated by thymic hyperplasia. Routine chest radiography revealed an abnormal opacity, and computed tomography revealed an anterior mediastinal tumor. At the initial visit to our institution, blood tests revealed hyperthyroidism with positive thyroid-stimulating hormone receptor antibodies, confirming the diagnosis of GD. As the patient opted for long-term antithyroid drug therapy, radioiodine therapy was administered. A computed tomography-guided biopsy revealed thymic hyperplasia. Following radioiodine therapy, the thyroid function normalized, and the tumor significantly shrank. Based on the pathology and clinical course, the patient was diagnosed with thymic hyperplasia secondary to GD, which regressed with conservative management.

Indexed as

Graves DiseaseRadiography, ThoracicThymus HyperplasiaAdultAntithyroid AgentsFemaleHumansIodine RadioisotopesTomography, X-Ray ComputedAntithyroid AgentsIodine Radioisotopesabnormal opacity on chest radiographyGraves' diseaseradioiodine therapysoluble interleukin-2 receptorthymic hyperplasia

Identifiers

PMID40803846
PMCPMC13019015

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.