Evidence map›Paper›PMID 40803770›Full record

SynthesisFamily medicine and community health2025

Global evidence on the effectiveness of task-shifting and task-sharing strategies for managing individuals with multimorbidity: systematic review and meta-analysis.

Enying Gong, Yutong Long, Xunliang Tong, Wai Yan Min Htike, Jiahui Wang, Shiqi Ni, Yueqing Wang, Zijun Wang, Lijing L Yan, Sumit Kane and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Family medicine and community health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Enying GongSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China gongenying@cams.cn lymyl@263.net.ORCID 0000-0003-2203-0369
Yutong LongSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-6460-6461
Xunliang TongDepartment of Pulmonary and Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Beijing, China.
Wai Yan Min HtikeGlobal Health Research Center, Duke Kunshan University, Kunshan, Jiangsu, China.ORCID 0009-0001-7284-9826
Jiahui WangSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Shiqi NiSchool of Public Health, Wuhan University, Wuhan, Hubei, China.
Yueqing WangSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-3676-5123
Zijun WangEvidence-Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu, China.
Lijing L YanGlobal Health Research Center, Duke Kunshan University, Kunshan, Jiangsu, China.ORCID 0000-0002-3029-0462
Sumit KaneNossal Institute for Global Health, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-4858-7344
Ruitai ShaoSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yanming LiDepartment of Pulmonary and Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Beijing, China gongenying@cams.cn lymyl@263.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTask-shifting and task-sharing strategies show promise for managing chronic diseases especially in low-income and middle-income countries (LMICs), though their effectiveness in multimorbidity management remains unclear. This study synthesised evidence on task-shifting and task-sharing strategies globally and assessed the impact on core health outcomes in multimorbidity management.

methodsWe conducted a systematic review and meta-analysis of global studies evaluating task-shifting and sharing interventions for individuals with multimorbidity. Six databases, including PubMed, Embase, Web of Science, Ovid (Medline), CINAHL and Cochrane Library, were searched for studies reporting the core outcomes of multimorbidity management in quality of life, mortality, hospitalisation, emergency department visits and symptoms of depression and anxiety. Random-effects models were used to calculate pooled effect sizes with heterogeneity assessed through subgroup and meta-regression analyses.

resultsFrom 8471 records, 36 studies from 14 countries were included, with only 5 conducted in LMICs. Twenty-one studies, encompassing 20 989 participants, were eligible for meta-analysis. More than half of the studies involved nurses as delegates, with some sharing the tasks with health professionals and about 10% of studies involved non-health professionals, including community healthcare workers as delegates to share the responsibility in caring for individuals with multimorbidity. Most studies were multicomponent, with 16.7% addressing all guideline-recommended aspects of multimorbidity management. By pooling the findings, task-shifting and task-sharing interventions were associated with a 27% reduction in mortality (OR: 0.73, 95% CI: 0.55 to 0.97, I²=0%), a modest improvement in quality of life (standardised mean difference (SMD): 0.1, 95% CI: 0.03 to 0.17, I²=47%) and reduced symptoms of depression (SMD: 0.27, 95% CI: -0.52 to -0.02, I²=90%), but showed no significant effect on hospitalisation, emergency visits or anxiety-related symptoms.

conclusionsSome evidence, although limited in existing research, indicates the great potential of task-shifting and task-sharing strategies in supporting management of multimorbidity. Further research is needed to optimise and adopt these interventions, particularly in LMICs where evidence remains scarce. PROSPERO REGISTRATION NUMBER: CRD42024526845.

Indexed as

MultimorbidityChronic DiseaseGlobal HealthHumansQuality of LifeCommunity Health ServicesDelivery of Health Care, IntegratedMultiple Chronic Conditions

Identifiers

PMID40803770
PMCPMC12352192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.