ArticleBMJ open2025
Rationale and methodology of a multicentric prospective cohort study on 'Longitudinal Effects of Air Pollution Exposure on Adolescent Lungs (APEAL)' in urban India: APEAL protocol.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionAir pollution is a significant global health concern, with studies from the USA and Europe linking long-term exposure to respiratory issues and poor school attendance in children. While Indian cities experience much higher pollution levels, the impact on lung development in Indian children remains unclear. This study aims to assess the burden of impaired lung function in Indian children and identify key factors contributing to pollution-induced lung injury. METHODS AND ANALYSIS: This longitudinal, prospective cohort study is conducted in four cities categorised by particulate matter 2.5 (PM ETHICS AND DISSEMINATION: The approval from individual site institutional review board (IRB) is obtained prior to initiation of the study from institutional ethics committee, St. John's Medical College and Hospital, Bangalore; institutional ethics committee, JSS Medical College, Mysore; institute ethics committee, Indian Institute of Technology Bombay and institute ethics committee, All India Institute of Medical Sciences. Findings from this study will be disseminated through conference presentations, peer-reviewed publications and establishment of normal age-appropriate lung function reference values for children living in urban India.
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