ArticleJournal of sport and health science2025
Intensity modifies the association between continuous bouts of physical activity and risk of mortality: A prospective UK Biobank cohort analysis.
Article in Journal of sport and health science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Waking-hour movement patterns and all-cause mortality: A multi-dimensional accelerometer analysis in the UK Biobank.Journal of exercise science and fitness · 2026Article
- Intensity-specific physical activity and mortality in 147,414 adults: a pooled accelerometer analysis.The international journal of behavioral nutrition and physical activity · 2026Article
- A Multimodal Framework for Organ- and Cell-Resolved Biological Aging and Longevity Intervention Discovery.medRxiv : the preprint server for health sciences · 2026Article
- Data from the UK Biobank demonstrates that increased brief, sporadic moderate-to-vigorous physical activity reduces mortality.Communications medicine · 2026Article
- Commentary on: Intensity modifies the association between continuous bouts of physical activity and risk of mortality: A prospective UK Biobank cohort analysis.Journal of sport and health science · 2025Article
- Opportunities for physical activity research in Puerto Rico: a review of the literature.Discover public health · 2025Review
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent evidence suggests continuous bouts of physical activity (PA) are associated with longevity. We hypothesized the risk of mortality would be lower when the most active minutes of the day were in a continuous bout.
methodsPA was assessed using accelerometery in UK Biobank participants. The intensity of the most active continuous (MX
resultsIn total, 94,541 participants (56.5% female) were included. Over a median (interquartile range) follow-up of 6.9 (6.3, 7.4) years, 2649 (2.8%) deaths occurred. Intensity moderated the association between how the most active minutes of the day were accumulated and mortality risk, expressed relative to sporadically accumulated moderate PA. If the most active minutes were of moderate intensity, the risk of mortality was halved for continuous compared to sporadic accumulation, irrespective of duration; if the most active minutes were of vigorous intensity, a continuous bout was associated with the lowest risk for durations under 5 min (e.g., 3 min: hazard ratio (HR) = 0.27, 95% confidence interval (95%CI): 0.21-0.34), while sporadic accumulation was associated with the lowest risk for durations beyond 5 min (HR = 0.11, 95%CI: 0.08-0.15 for the most active 20 min).
conclusionOptimal PA patterns for reducing mortality differ by intensity and duration. For moderate-intensity PA, a lower mortality risk may be optimized by prioritizing continuous PA for up to 20 min. However, for vigorous-intensity PA, multiple short bouts (<5 min) may be optimal. This suggests tailored PA recommendations may enhance longevity benefits.
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