ArticleEuropean journal of dentistry2026
Clinical Outcomes of rhBMP-2-Loaded Collagen Sponge for Alveolar Ridge Preservation: A Pilot Study.
Article in European journal of dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alveolar ridge preservation versus unassisted socket healing following tooth extraction: a systematic review of controlled clinical studies and meta-analysis of randomised trials.Oral and maxillofacial surgery · 2026Pooled it
- Comparative Analysis of Bone Remodeling Dynamics and Bone Vitality Following Standard Bone Augmentation Procedures: A Review.Journal of functional biomaterials · 2026Review
- Optimizing rhBMP-2 Therapy for Bone Regeneration: From Safety Concerns to Biomaterial-Guided Delivery Systems.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Alveolar bone resorption following tooth extraction poses a significant clinical challenge. While various ridge preservation techniques exist, limitations remain. Recombinant human bone morphogenetic protein-2 (rhBMP-2) delivered via an absorbable collagen sponge (ACS) has shown promise in bone augmentation. This pilot randomized controlled trial aimed to evaluate the efficacy of ACS combined with rhBMP-2 for alveolar ridge preservation in maintaining ridge dimensions after tooth extraction. Materials and Methods: This pilot randomized controlled trial enrolled 11 participants with 16 extraction sites, randomized to either the intervention (ACS/rhBMP-2) or the control (empty socket) group. The Statistical Analysis: Data were presented as mean ± standard deviation. A linear mixed model was used to compare dimensional changes over time between the two groups. A Results: The Conclusions: The application of ACS combined with rhBMP-2 is an effective approach for mitigating buccal bone resorption after tooth extraction. This intervention is clinically significant as it preserves critical buccal plate height, potentially reducing the need for further augmentation prior to implant placement, even though it does not prevent overall ridge width collapse.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.