Evidence map›Paper›PMID 40803037›Full record

ArticleVascular2026

Three-stage extensive aortic substitution in a young man with a variant of uncertain significance in myosin heavy chain 11 gene.

Federico Pascucci, Tommaso Donati, Albino Vallabini, Mauro Cassese, Yamume Tshomba

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Vascular, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Federico PascucciVascular Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore - Roma, Italy.ORCID 0000-0003-3372-7962
Tommaso DonatiVascular Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore - Roma, Italy.
Albino VallabiniCardiac Surgery Unit, Casa Sollievo Della Sofferenza IRCCS - San Giovanni Rotondo, Italy.
Mauro CasseseCardiac Surgery Unit, Casa Sollievo Della Sofferenza IRCCS - San Giovanni Rotondo, Italy.
Yamume TshombaVascular Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore - Roma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundNon-syndromic hereditary aortic diseases are caused by mutations in genes encoding for connective tissue components, involving structural integrity of aortic tissue. Amongst them, MYH11 gene mutation is a known causative factor for aortic diseases, especially in young patients.Research DesignWe report the case of a 37 years-old male which came to our attention for an acute DeBakey type I aortic dissection. In three different operations he was submitted to a total aortic substitution with a Bentall operation, a Frozen Elephant Trunk and a Thoracoabdominal Aortic open repair. During the last two operations particular technical tips, which are reported in this work, have been adopted to optimize surgical strategy.

Indexed as

Aortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCardiac MyosinsMutationMyosin Heavy ChainsAdultAortographyGenetic Predisposition to DiseaseHumansMalePhenotypeTreatment OutcomeCardiac MyosinsMYH11 protein, humanMyosin Heavy Chainsaortic dissectionConnective tissue diseasesMYH11thoraco-abdominal aortic aneurysm

Identifiers

PMID40803037
PMCPMC13195059

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.