Evidence map›Paper›PMID 40802591›Full record

ReviewNutrition reviews2026

Rice Bran: A Comprehensive Review of Phytochemicals and Bioactive Components With Therapeutic Potential and Health Benefits.

Mir Zahoor Gul, Prajna Priyadarshini Das, Komaragiri Rajesh Babu, Sheila Juarez-Colunga, Annika M Weber, Basma Yoosuf, Aneesha Susan Alex, Rakesh K Srivastava, Balram Marathi, Swati Patel and 2 more

Abstract readReview
In one paragraph

Review in Nutrition reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mir Zahoor GulDepartment of Plant Sciences, School of Life Sciences, University of Hyderabad, Prof. C. R. Rao Road, Hyderabad, Telangana 500046, India.ORCID 0000-0002-1088-4255
Prajna Priyadarshini DasDepartment of Plant Sciences, School of Life Sciences, University of Hyderabad, Prof. C. R. Rao Road, Hyderabad, Telangana 500046, India.ORCID 0000-0003-0989-4197
Komaragiri Rajesh BabuDepartment of Plant Sciences, School of Life Sciences, University of Hyderabad, Prof. C. R. Rao Road, Hyderabad, Telangana 500046, India.ORCID 0000-0003-1282-2151
Sheila Juarez-ColungaDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, United States.ORCID 0000-0001-5136-4515
Annika M WeberDepartment of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO 80523, United States.ORCID 0000-0002-7234-879X
Basma YoosufDepartment of Biosciences, Mar Athanasios College for Advance Studies, Thiruvalla, Kerala 689101, India.
Aneesha Susan AlexDepartment of Biosciences, Mar Athanasios College for Advance Studies, Thiruvalla, Kerala 689101, India.
Rakesh K SrivastavaGenomics, Pre-breeding, and Bioinformatics (GPB), Accelerated Crop Improvement (ACI), International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Patancheru, Telangana 502324, India.ORCID 0000-0001-6715-0386
Balram MarathiProfessor Jayashankar Telangana State Agricultural University, Rajendranagar, Hyderabad 500030, India.ORCID 0000-0003-1747-6438
Swati PatelDivision of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States.
Elizabeth P RyanDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, United States.ORCID 0000-0002-1577-0919
Irfan A GhaziDepartment of Plant Sciences, School of Life Sciences, University of Hyderabad, Prof. C. R. Rao Road, Hyderabad, Telangana 500046, India.ORCID 0009-0000-4534-0701

Funding

CSU Infectious Disease Research and Response Training ProgramT32AI162691 · NIAID · COLORADO STATE UNIVERSITY · PI DEAN, GREGG A · 2021 to 2025
$2.1M
Rice bran in ready-to-use therapeutic foods for microbiota-targeted treatment of childhood malnutritionR21HD113211 · NICHD · COLORADO STATE UNIVERSITY · PI RYAN, ELIZABETH P · 2023 to 2023
$417k
Department of BiotechnologyIAG LabNational Institute of Allergy and Infectious Diseases T32AI162691National Science Foundation 1828902NIAID NIH HHS T32 AI162691NICHD NIH HHS R21 HD113211NIH HHS R21HD113211-01School of Life Sciences, University of Hyderabad DBT-BT/INF/22/SP41176/2020The Colorado State University
6 · The paper itself

Abstract

Rice bran is a by-product of paddy rice milling that has emerged as a versatile source of nutritional, preventive, and therapeutic compounds. Rich with diverse bioactive elements, rice bran serves as a nontraditional functional food ingredient with health promoting attributes. The nutritional profile of rice bran compared to those of other cereal grains is inclusive of energy-providing carbohydrates, essential vitamins and minerals, and amino and fatty acids, as well as unique phytochemicals. The composition of rice bran consists of an array of phytosterols, prebiotics, tocotrienols, tocopherols, flavonoids, and phenolic compounds that contribute antioxidant, anti-inflammatory, and antimicrobial activities. A unique rice bran compound is γ-oryzanol, which is widely recognized for supporting the immune system, regulating blood lipids, and protecting against some types of cancer. In this review we have summarized the multifaceted potential of rice bran for reducing diarrhea and controlling diabetes and cardiometabolic disease, as well as preventing or controlling progression of cancer. Rice bran-mediated regulation of bowel function through prebiotics and soluble and insoluble fiber acts synergistically in lowering gut inflammation through microbiota and regulating the metabolism of lipids and proteins that are important for health. The capacity of rice bran to enhance nutritional status in connection with the prevention and management of chronic diseases merits greater attention in the food product marketplace. In this comprehensive overview of rice bran as a functional food for human health, we have also included its medical food potential for holistic well-being, health promotion, and disease prevention.

Indexed as

Dietary FiberOryzaPhytochemicalsAntioxidantsFunctional FoodHumansNutritive ValuePhenylpropionatesPrebioticsAntioxidantsDietary Fibergamma-oryzanolPhenylpropionatesPhytochemicalsPrebioticsbioactive compoundschronic diseasedisease preventionhuman healthOryza sativaphytochemicalsrice bran

Identifiers

PMID40802591
PMCPMC13250452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.