Evidence map›Paper›PMID 40802283›Full record

ArticleJournal of bacteriology2025

Sequence variability of BamA and FadL candidate vaccinogens suggests divergent evolutionary paths of

Everton B Bettin, Farhang Aghakhanian, Christopher M Hennelly, Wentao Chen, Timothy C Davenport, Simon T Hackl, Andre A Grassmann, Fabio Vargas-Cely, Sebastián Silva, Jonny A García-Luna and 18 more

Abstract read
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. The Global Syphilis Epidemic: Turning the Tide.Sexually transmitted diseases · 2026
    Article
  4. Detection ofMicrobiology spectrum · 2026
    Article
  5. Review
  6. TheJornal brasileiro de doencas sexualmente transmissiveis : DST · 2026
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Everton B BettinUConn Health, Farmington, Connecticut, USA.ORCID 0000-0001-5095-2198
Farhang AghakhanianThe University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Christopher M HennellyThe University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Wentao ChenDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID 0000-0002-4062-3865
Timothy C DavenportDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.
Simon T HacklInstitute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Baden-Württemberg, Germany.
Andre A GrassmannUConn Health, Farmington, Connecticut, USA.
Fabio Vargas-CelyDivision of Hematology and Medical Oncology, Mayo Clinic, Phoenix, Arizona, USA.
Sebastián SilvaCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Pance, Valle del Cauca, Colombia.
Jonny A García-LunaCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Pance, Valle del Cauca, Colombia.
Lady G RamirezCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Pance, Valle del Cauca, Colombia.
Yinbo JiangDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Ligang YangDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Heping ZhengDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Bin YangDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Petra PospíšilováCzech Republic Department of Biology, Faculty of Medicine, Masaryk University, Brno, South Moravian Region, Czechia.
David ŠmajsCzech Republic Department of Biology, Faculty of Medicine, Masaryk University, Brno, South Moravian Region, Czechia.ORCID 0000-0002-4176-3464
Mitch M MatogaUNC Project-Malawi, Lilongwe, Central Region, Malawi.
Irving F HoffmanThe University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Eduardo López-MedinaCentro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Pance, Valle del Cauca, Colombia.
Kay NieseltInstitute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Baden-Württemberg, Germany.
M Anthony MoodyDuke University Medical Center, Durham, North Carolina, USA.
Arlene C SeñaThe University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Juan C SalazarUConn Health, Farmington, Connecticut, USA.
Jonathan B ParrThe University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Melissa J CaimanoUConn Health, Farmington, Connecticut, USA.ORCID 0000-0003-1170-4102
Kelly L HawleyUConn Health, Farmington, Connecticut, USA.ORCID 0000-0001-8587-1662
Justin D RadolfUConn Health, Farmington, Connecticut, USA.ORCID 0000-0002-9341-6712

Funding

Prevalence of syphilis and other sexually transmitted infections in men and transgender women who have sex with men in Cali, ColombiaU19AI144177 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SALAZAR, JUAN C · 2019 to 2023
$11.2M
INFECTIOUS DISEASE PATHOGENESIS TRAININGT32AI007151 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JULIANO, JONATHAN J · 1985 to 2024
$5.5M
Vector/Host-Parasite Interface of Leishmaniasis in ColombiaD43TW006589 · FIC · YALE UNIVERSITY · PI GORE SARAVIA, NANCY, TSCHUDI, CHRISTIAN · 2003 to 2024
$4.3M
FIC NIH HHS D43 TW006589FIC NIH HHS D43TW006589Gates Foundation INV-036560National Institute of Allergy and Infectious Diseases T32AI007151National Institute of Allergy and Infectious Diseases U19AI144177Next Generation Foundation LX22NPO5103NIAID NIH HHS T32 AI007151NIAID NIH HHS U19 AI144177Wellcome TrustWellcome Trust 214641/Z/18/Z
6 · The paper itself

Abstract

Knowledge of

Indexed as

Bacterial Outer Membrane ProteinsBacterial VaccinesEvolution, MolecularGenetic VariationTreponema pallidumChinaColombiaHumansMalawiPhylogenySyphilisBacterial Outer Membrane ProteinsBacterial Vaccinesouter membrane proteinsprotein variabilitysyphilisvaccineswhole-genome sequencing

Identifiers

PMID40802283
PMCPMC12369335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.