ReviewMolecular biology of the cell2025
Please inhibit responsibly: Natural and synthetic actin toxins as useful tools in cell biology.
Review in Molecular biology of the cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- A single-molecule reporter of membrane-proximal actin detects rapid remodeling upon B cell receptor clustering.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The actin cytoskeleton drives many critical cell functions, including motility, division, and vesicular trafficking. To fulfill these functions, actin networks are dynamic and tightly regulated by dozens of proteins that cause actin to assemble and disassemble at the proper time and place. Given the importance of actin to a cell's biology, it is not surprising that some organisms produce toxins that target actin dynamics to incapacitate prey, win turf wars, or as a defense against predation. For decades, cell biologists have leveraged these toxins and synthesized new ones to cause defects in the structure and function of the actin cytoskeleton. Here, we provide an overview of commonly used actin inhibitors and their origins, as well as best practices for their use in biological studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.