Evidence map›Paper›PMID 40802184›Full record

Trial reportJAMA network open2025

Video and Infographic Messages From Primary Care Physicians and Influenza Vaccination Rates: A Randomized Clinical Trial.

Peter G Szilagyi, Emma J Clark, O Kenrik Duru, Alejandra Casillas, Michael K Ong, Sitaram Vangala, Chi-Hong Tseng, Christina Albertin, Sharon G Humiston, Mindy K Ross and 7 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06062264 (Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient Portal RCT 6), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06062264 nacompletednot on this map

Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient Portal RCT 6

TypeinterventionalSponsorUniversity of California, Los AngelesRan2023 to 2024Enrolled22,233ConditionsInfluenza, Respiratory Tract InfectionsArmsPortal-based Video Message, Portal-based Infographic Message
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Peter G SzilagyiDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California, Los Angeles.
Emma J ClarkDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California, Los Angeles.
O Kenrik DuruDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles.
Alejandra CasillasDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles.
Michael K OngDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles.
Sitaram VangalaDepartment of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles.
Chi-Hong TsengDepartment of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles.
Christina AlbertinDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California, Los Angeles.
Sharon G HumistonImmunize.org, St Paul, Minnesota.
Mindy K RossDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California, Los Angeles.
Sharon EvansDepartment of Information Services and Solutions, UCLA Health System, Los Angeles, California.
Arjun KumarDepartment of Information Services and Solutions, UCLA Health System, Los Angeles, California.
Ilona ChakarianDepartment of Information Services and Solutions, UCLA Health System, Los Angeles, California.
Michael SloyanDepartment of Information Services and Solutions, UCLA Health System, Los Angeles, California.
Craig R FoxDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles.
Cynthia M RandDepartment of Pediatrics, University of Rochester Medical Center, Rochester, New York.
Carlos LernerDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California, Los Angeles.

Funding

Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient PortalR01AI135029 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SZILAGYI, PETER G · 2018 to 2022
$3.7M
NIAID NIH HHS R01 AI135029
6 · The paper itself

Abstract

Importance: Influenza vaccination coverage in the US is low, due largely to vaccine hesitancy. Personalized messages from trusted physicians may raise vaccination rates. Objective: To evaluate the effects of physician-created videos and infographics containing physician photographs on influenza vaccination rates. Design, Setting, and Participants: This 3-arm randomized clinical trial included patients from 6 months to older than 65 years of age served by 21 primary care physicians in 21 practices at UCLA Health who were listed in the electronic health record as not receiving influenza vaccination between October 31, 2023, and April 1, 2024. Intervention: Patients within each physician patient population were randomized to receive usual care or a physician-created video or an infographic with their physician's photograph encouraging receipt of influenza vaccinations. Primary care physicians used a suggested script to create a brief video with their smartphone or a video conference recording, or an infographic containing their photograph and a similar script was created, both encouraging patients to receive influenza vaccinations. The video or infographic was sent via the patient portal up to 3 times (October, November, and December). Main Outcomes and Measures: All analyses used the evaluable patient population. The primary outcome was end-of-season influenza vaccination rates by Aril 1, 2024. A secondary outcome was timely vaccination by December 31, 2023. Results: Among 22 233 patients, 3200 were children younger than 18 years (14.4%), 14 704 were adults 18 to 64 years of age (66.1%), and 4329 were adults 65 years or older (19.5%); 13 973 (62.8%) were female. Overall, 18 878 patients (84.9%) had private insurance. The rates of influenza vaccination across the entire study population by April 1, 2024, were 3479 of 7417 (46.9%) for usual care, 3557 of 7410 (48.0%) for the video arm, and 3518 of 7406 (47.5%) for the infographic arm. Neither intervention had significantly higher rates of vaccination than usual care (adjusted risk ratio, 1.03 [95% CI, 1.00-1.06] for the video group; adjusted risk ratio, 1.02 [95% CI, 0.99-1.06] for the infographic group). In the post hoc analysis, children in both intervention arms had higher vaccination rates by April 1, 2024: 618 of 1058 children in the video group (58.4%) (P < .001) and 598 of 1085 children in the infographics group (55.1%), each compared with 576 of 1057 (54.5%) in the usual care group (P = .04). Conclusions and Relevance: In this randomized clinical trial, neither physician-created videos nor infographics increased influenza overall vaccination rates by April 1, 2024. However, among children, both interventions were effective by end of influenza season. Messages personalized by physicians may represent a potential strategy to improve influenza vaccination among children, but further innovations are needed across the entire age spectrum. Trial Registration: ClinicalTrials.gov Identifier: NCT06062264.

Indexed as

Influenza, HumanInfluenza VaccinesPhysicians, Primary CareVaccinationVaccination CoverageVideo RecordingAdolescentAdultAgedChildChild, PreschoolFemaleHumansInfantMaleMiddle AgedInfluenza Vaccines

Identifiers

PMID40802184
PMCPMC12351418

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.