ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025
Inflammatory hematological ratios and subclinical microvascular changes of fundus in Behçet disease.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purposeThis study aimed to investigate the relationship between inflammatory hematological ratios, specifically the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR), and microvascular changes of the fundus in Behçet disease (BD) including non-ocular and quiescent ocular BD patients.
methodsConducted as a retrospective, single-center study, patients diagnosed with BD were categorized into non-ocular and quiescent ocular BD groups. Systemic inflammatory hematological ratios were assessed through laboratory evaluations, while retinal and choroidal parameters were measured using optical coherence tomography (OCT) and OCT angiography (OCTA).
resultsTwenty-five patients were included, with 12 in the non-ocular and 13 in the quiescent ocular BD group. The quiescent ocular BD group exhibited significantly higher minimum PLR, foveal avascular zone area (FAZa), and perimeter (FAZp). Additionally, significant correlations were observed between the minimum PLR and central retinal thickness (CRT), FAZa, and FAZp. No factors were significantly associated with visual acuity in regression analysis.
conclusionInflammatory hematological ratios such as the minimum PLR may serve as a promising biomarker for detecting subclinical microvascular changes in BD. These findings highlight the importance of integrating inflammatory hematological ratios with OCT, OCTA metrics for early detection of ocular impairment in BD, potentially guiding proactive management to prevent irreversible ocular damage.
Indexed as
Identifiers
40802042What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.