Evidence map›Paper›PMID 40802008›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Topical oleic acid reduces nociception and inflammation in a UVB radiation-induced sunburn model in mice.

Patrick Tuzi Serafini, Evelyne Silva Brum, Gabriela Becker, Amanda Favarin, Indiara Brusco, Sara Marchesan Oliveira

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patrick Tuzi Serafini *Graduate Program in Biological Sciences: Toxicological Biochemistry, Centre of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Evelyne Silva Brum *Graduate Program in Biological Sciences: Toxicological Biochemistry, Centre of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Gabriela BeckerGraduate Program in Biological Sciences: Toxicological Biochemistry, Centre of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Amanda FavarinGraduate Program in Biological Sciences: Toxicological Biochemistry, Centre of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Indiara BruscoGraduate Program in Biological Sciences: Toxicological Biochemistry, Centre of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Sara Marchesan OliveiraGraduate Program in Biological Sciences: Toxicological Biochemistry, Centre of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil. saramarchesan@ufsm.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico #150611/2022-6Conselho Nacional de Desenvolvimento Científico e Tecnológico 152071/2024-5Conselho Nacional de Desenvolvimento Científico e Tecnológico Grants #309404/2023-1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior #88882.182148/2018-01Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.139801/2025-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior #88887.568915/2020-00Coordenação de Aperfeiçoamento de Pessoal de Nível Superior #88887.952927/2024-00Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Grant #21/2551-0001966-2
6 · The paper itself

Abstract

Injuries resulting from sun exposure constitute a public health problem and are characterised by pain, oedema, and erythema. Although generally effective, the available drugs for treating burns cause adverse effects that limit their use, demonstrating the need for new pharmacological options. Natural products, such as oleic acid (OA), which are naturally present in cellular structures and the diet, appear promising therapeutic alternatives due to their antinociceptive, anti-inflammatory, and antioxidant actions. Thus, we evaluated the effects of topical OA (0.3%, 1%, and 3%) in a sunburn model induced by UVB radiation (0.75 J/cm

Indexed as

AnalgesicsAnti-Inflammatory AgentsInflammationNociceptionOleic AcidSunburnUltraviolet RaysAdministration, TopicalAnimalsDexamethasoneDisease Models, AnimalEdemaHyperalgesiaMaleMiceReactive Oxygen SpeciesAnalgesicsAnti-Inflammatory AgentsDexamethasoneOleic AcidReactive Oxygen SpeciesAnalgesicsAnti-inflammatoriesNatural compoundOedemaPain

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.