ArticlePlant cell reports2025
Comprehensive analysis of bHLH genes in wheat and functional characterization of TabHLH319 in salt tolerance.
Article in Plant cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- bHLH Transcription Factors in Cereal Crops: Diverse Functions in Regulating Growth, Development and Stress Responses.International journal of molecular sciences · 2025Review
- Genome-Wide Identification and Expression Analysis of the bHLH Transcription Factor Family inGenes · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
key messageWe identified 479 putative TabHLH genes in Zhou8425B and systematically analyzed their functions. TabHLH319 was revealed as a key salt tolerance gene significantly associated with yield-related traits. The basic helix-loop-helix (bHLH) transcription factors represent one of the largest gene families in plants, playing vital roles in development and stress responses. Here, we bioinformatically identified 479 bHLH genes in the high-quality genome of the wheat core parent Zhou8425B and classified them into 13 subfamilies. We investigated their gene structures and computed their physicochemical properties and phylogenetic relationships. RNA-seq data from 12 tissues revealed diverse and tissue-specific expression patterns, several bHLH genes were identified as responsive to various environmental stresses, among which TabHLH319 was implicated in salt tolerance. Sequence comparison between Zhou8425B and Chinese Spring (CS) revealed a nonsynonymous SNP in the exon of TabHLH319. Moreover, a 57-bp insertion in the promoter region specific to Zhou8425B. A molecular marker targeting the InDel was developed and used to genotype a recombinant inbred line (RIL) population derived from Zhou8425B × CS. Dual-luciferase assays demonstrated that this 57-bp insertion significantly enhanced promoter activity under salt stress, explaining the elevated expression of TabHLH319
Indexed as
Identifiers
40801962What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.