Evidence map›Paper›PMID 40801622›Full record

ArticleCells2025

From Development to Regeneration: Insights into Flight Muscle Adaptations from Bat Muscle Cell Lines.

Fengyan Deng, Valentina Peña, Pedro Morales-Sosa, Andrea Bernal-Rivera, Bowen Yang, Shengping Huang, Sonia Ghosh, Maria Katt, Luciana Andrea Castellano, Lucinda Maddera and 4 more

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chiropteran (Animals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Fengyan DengStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Valentina PeñaStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0009-0004-4964-1527
Pedro Morales-SosaStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0009-0009-6479-4149
Andrea Bernal-RiveraStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Bowen YangStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Shengping HuangStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Sonia GhoshStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Maria KattStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Luciana Andrea CastellanoStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0000-0002-3250-6116
Lucinda MadderaStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Zulin YuStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Nicolas RohnerStowers Institute for Medical Research, Kansas City, MO 64110, USA.
Chongbei ZhaoStowers Institute for Medical Research, Kansas City, MO 64110, USA.ORCID 0000-0002-7224-5600
Jasmin CamachoStowers Institute for Medical Research, Kansas City, MO 64110, USA.

Funding

Starvation resistance and resilience of metabolic dysfunction in cavefishDP2AG071466 · NIA · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ROHNER, NICOLAS · 2020 to 2020
$2.5M
Burroughs Wellcome Fund G-1022339Howard Hughes Medical Institute GT15991National Science Foundation 2109717NIA NIH HHS DP2 AG071466NIH HHS 1DP2AG071466-05
6 · The paper itself

Abstract

Skeletal muscle regeneration depends on muscle stem cells, which give rise to myoblasts that drive muscle growth, repair, and maintenance. In bats-the only mammals capable of powered flight-these processes must also sustain contractile performance under extreme mechanical and metabolic stress. However, the cellular and molecular mechanisms underlying bat muscle physiology remain largely unknown. To enable mechanistic investigation of these traits, we established the first myoblast cell lines from the pectoralis muscle of

Indexed as

Adaptation, PhysiologicalChiropteraFlight, AnimalMuscle DevelopmentMuscle, SkeletalRegenerationAnimalsCell DifferentiationCell LineMyoblastsTranscriptomebatCDK4flight muscle biologyhTERTmyoblast cell linemyotubeproliferation and differentiationregeneration

Identifiers

PMID40801622
PMCPMC12346413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.