Evidence map›Paper›PMID 40801592›Full record

ArticleCells2025

Formyl Peptide Receptors 1 and 2: Essential for Immunomodulation of Crotoxin in Human Macrophages, Unrelated to Cellular Entry.

Luciana de Araújo Pimenta, Ellen Emi Kato, Ana Claudia Martins Sobral, Evandro Luiz Duarte, Maria Teresa Moura Lamy, Kerly Fernanda Mesquita Pasqualoto, Sandra Coccuzzo Sampaio

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Crotoxin fromFrontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luciana de Araújo PimentaLaboratory of Pathophysiology, Butantan Institute, Sao Paulo 05503-900, Brazil.
Ellen Emi KatoLaboratory of Pathophysiology, Butantan Institute, Sao Paulo 05503-900, Brazil.ORCID 0000-0001-5344-6071
Ana Claudia Martins SobralCenter for Contaminants, Adolfo Lutz Institute, Sao Paulo 01246-000, Brazil.
Evandro Luiz DuarteInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.ORCID 0000-0001-5550-6541
Maria Teresa Moura LamyInstitute of Physics, University of Sao Paulo, Sao Paulo 05508-090, Brazil.ORCID 0000-0001-6616-6546
Kerly Fernanda Mesquita PasqualotoLIM-14, Faculty of Medicine, University of Sao Paulo, Sao Paulo 05508-000, Brazil.ORCID 0000-0001-6901-7829
Sandra Coccuzzo SampaioLaboratory of Pathophysiology, Butantan Institute, Sao Paulo 05503-900, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico - CNPq/Master (Demanda So-cial) 158259/2018-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/11161-6National Council for Scientific and Technological Development 301685/2017-7
6 · The paper itself

Abstract

Crotoxin (CTX), the main toxin in

Indexed as

CrotoxinImmunomodulationMacrophagesReceptors, Formyl PeptideHumansPhagocytosisReactive Oxygen SpeciesReceptors, LipoxinSignal TransductionTHP-1 CellsCrotoxinFPR1 protein, humanFPR2 protein, humanReactive Oxygen SpeciesReceptors, Formyl PeptideReceptors, Lipoxincrotoxinformyl peptides receptorsimmunomodulationin silico studyinternalizationmacrophages

Identifiers

PMID40801592
PMCPMC12345708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.