ArticleJournal of periodontal & implant science2026
Profilometric and radiographic analyses after early implant placement in sites with ridge preservation or spontaneous healing: 3-year follow-up of an exploratory randomized controlled trial.
Article in Journal of periodontal & implant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
Funding
Abstract
purposeThe aim of this exploratory randomized controlled clinical trial was to compare profilometric and radiographic changes following early implant placement in sites treated with alveolar ridge preservation versus spontaneous healing (SH). Additionally, the study aimed to investigate clinical parameters of the implants up to 3 years following crown insertion.
methodsThirty-five patients exhibiting either intact buccal bone plates or buccal dehiscence of up to 50% after single-tooth extraction of incisors, canines, or premolars were enrolled. Participants were randomly assigned to 1 of 3 groups: 1) deproteinized bovine bone mineral with 10% collagen covered by a collagen matrix (DBBM-C/CM), 2) deproteinized bovine bone mineral with 10% collagen alone (DBBM-C), or 3) SH. Implant placement occurred 8 weeks post-extraction. Profilometric analyses were performed utilizing impressions and digital scans. Patients underwent follow-up assessments for up to 3 years (FU-3Y) after the final crown insertion (fixed dental prosthesis insertion, FDPi).
resultsThe median contour changes between FDPi and FU-3Y were -0.23 mm for DBBM-C/CM, -0.21 mm for DBBM-C, and -0.33 mm for SH, demonstrating a statistically significant reduction over 3 years in all 3 groups (
conclusionsThe FU-3Y of this randomized clinical trial revealed stable clinical parameters and marginal bone levels in all evaluated groups. Although minor contour reductions were noted in all groups, these changes were deemed clinically acceptable.
trial registrationGerman Clinical Trials Register Identifier: DRKS00009496.
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