ArticleMolecular pharmaceutics2025
Charged Particle Dynamics in Dry Powder Inhalers.
Article in Molecular pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mechanism of interpleat channel blockage in pleated filters during dust loading.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanisms for the growth of particles in a stream of aerosolised inhalation powders have been investigated computationally using experimentally measured stream compositions. Many-body electrostatic theory has been incorporated into classical particle dynamics simulations to describe the aggregation of charged, fine powder particles in the single and dual stream geometry of an inhaler. The simulations use experimental bipolar charge measurements recorded using a Dekati BOLAR as input. Evidence of a subtle relationship between charge and the dynamics of particle growth contributes to our understanding of the electrostatics and many-body interactions in inhalation powders. It is found that certain combinations of particle size and charge result in a scavenging process whereby small particles, which may be therapeutic, aggregate with large particles to become ineffective due to an overall increase in size. This process may have important implications for design of dry powder inhaler devices.
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Registered trials
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