Evidence map›Paper›PMID 40801175›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2025

Stimuli-Responsive Materials for Biomedical Applications.

Adriana Teixeira do Nascimento, Paul R Stoddart, Toon Goris, Miriam Kael, Richard Manasseh, Karen Alt, Jurie Tashkandi, Byung Chul Kim, Simon E Moulton

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
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  4. [Research progress on the application of pollen in the biomedical field].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
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  14. Actuation of Cell Layers in Three Dimensions.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
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  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adriana Teixeira do NascimentoDepartment of Engineering Technologies, School of Engineering, Swinburne University of Technology, Victoria, 3122, Australia.
Paul R StoddartDepartment of Engineering Technologies, School of Engineering, Swinburne University of Technology, Victoria, 3122, Australia.
Toon GorisDepartment of Engineering Technologies, School of Engineering, Swinburne University of Technology, Victoria, 3122, Australia.
Miriam KaelDepartment of Engineering Technologies, School of Engineering, Swinburne University of Technology, Victoria, 3122, Australia.
Richard ManassehDepartment of Mechanical & Product Design Engineering, School of Engineering, Swinburne University of Technology, Victoria, 3122, Australia.
Karen AltNanoTheranostics Laboratory, The School of Translational Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, 3800, Australia.
Jurie TashkandiNanoTheranostics Laboratory, The School of Translational Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, 3800, Australia.
Byung Chul KimDepartment of Advanced Components and Materials Engineering, Sunchon National University, 255, Jungang-ro, Suncheon-si, Jellanam-do, 57922, Republic of Korea.
Simon E MoultonDepartment of Engineering Technologies, School of Engineering, Swinburne University of Technology, Victoria, 3122, Australia.ORCID 0000-0002-8320-3852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimuli-responsive materials (SRMs) are materials that change properties when exposed to external or internal stimuli. They respond to physiological changes within cells and tissues, as well as external triggers including light, magnetic fields, ultrasound, and electricity. In medicine, SRMs have diverse applications spanning drug delivery, tissue engineering, and diagnostics. They enable targeted drug release at specific times and locations, facilitate tissue generation and repair, and enhance disease detection capabilities. Beyond medical uses, SRMs are employed in smart coatings and artificial muscle systems. The breadth of biomedical applications for SRMs is extensive, generating substantial research into novel and innovative material development. Challenges in creating safe and efficient SRMs for medical treatments have driven innovative approaches in two key areas: functionalizing and modifying naturally occurring materials and developing new synthetic nanomaterials. The complexity of producing effective SRMs has necessitated creative solutions to overcome safety and efficiency barriers in medical applications. This ongoing research continues to expand the potential therapeutic uses of these responsive materials. This review examines literature focused on SRM development for external stimuli responses, particularly light, magnetic fields, ultrasound, and electricity, rather than covering the complete spectrum of stimuli-responsive applications.

Indexed as

Biocompatible MaterialsAnimalsDrug Delivery SystemsHumansLightMagnetic FieldsTissue EngineeringBiocompatible Materialsbiomedicalnanomaterialstimulus responsive

Identifiers

PMID40801175
PMCPMC12422095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.