Evidence map›Paper›PMID 40801120›Full record

ArticleEuropean stroke journal2025

Functional outcome, return to work and quality of life in patients with non-aneurysmal subarachnoid hemorrhage.

Wouter J Dronkers, Menno R Germans, René Post, Bert A Coert, Jonathan M Coutinho, René van den Berg, William Peter Vandertop, Dagmar Verbaan

Abstract read
In one paragraph

Article in European stroke journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wouter J DronkersDepartment of Neurosurgery, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0001-7684-1787
Menno R GermansDepartment of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-2185-4526
René PostDepartment of Neurosurgery, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Bert A CoertDepartment of Neurosurgery, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Jonathan M CoutinhoAmsterdam Neuroscience Center, Neurovascular Disease, Amsterdam, The Netherlands.ORCID 0000-0002-8284-982X
René van den BergAmsterdam Neuroscience Center, Neurovascular Disease, Amsterdam, The Netherlands.ORCID 0000-0002-8791-8791
William Peter VandertopDepartment of Neurosurgery, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Dagmar VerbaanDepartment of Neurosurgery, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNon-aneurysmal, non-traumatic subarachnoid hemorrhage (nSAH) refers to cases where a causative aneurysm cannot be identified. We studied 6-months' outcomes in nSAH patients. PATIENTS AND

methodsFrom a prospective SAH registry of all nSAH patients admitted between 2012 and 2023, relevant complications and outcomes were collected. Functional outcome and return-to-work at 6 months were assessed using the modified Rankin Scale (mRS), quality of life with the EuroQol-5Dimensions (EQ-5D) and Hospital Anxiety and Depression Scale (HADS), and an institutional 14-item questionnaire for assessment of residual symptoms.

results325 consecutive nSAH patients were included (192 non-perimesencephalic, non-aneurysmal subarachnoid hemorrhage (NPSAH); 133 perimesencephalic subarachnoid hemorrhage (PMSAH)). 303 (93%; 180 NPSAH and 123 PMSAH) were available at follow-up (7 patients died). Favorable functional outcome (mRS-score 0-2) was reported in 271 (89%) patients and did not differ between NPSAH- and PMSAH. One hundred forty-one (77%) patients returned to work, whereas only 71 (39%) patients reached their previous level of work. PMSAH patients were more likely to return to work (68/96 (71%) NPSAH and 73/87 (84%) PMSAH, respectively, DISCUSSION AND

conclusionThis study reveals that the majority of nSAH patients reports residual symptoms and did not return to their previous level of work at 6 months follow-up, despite a favorable functional outcome. These findings nuance the perception of a good outcome, as suggested in previous studies, warranting further research on possible rehabilitative interventions and counseling in these patients.

Indexed as

Complicationsneurologyoutcomereturn to workstrokesubarachnoid hemorrhage

Identifiers

PMID40801120
PMCPMC12350299

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